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页数:5页
时间:2019-05-24
《右美托咪定辅助强化麻醉应用于臂丛神经阻滞不全时的效果观察》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、万方数据国隧盛醛堂皇复蒸盘查垫!≥生8旦筮3垒鲞筮§翅!匹』△!!壁垒基曼曼塑:△坠鲤鲢2Q13:!!!:丝:盟丛687·论著·右美托咪定辅助强化麻醉应用于臂丛神经阻滞不全时的效果观察缪文丽张元信王德明武春敏曲彦亮温宝磊【摘要】目的观察右美托咪定(dexmedetomidine,DEX)在臂丛神经阻滞不全时的辅助强化麻醉效果及安全性评价。方法将臂丛神经阻滞麻醉后出现阻滞不全的手外伤择期手术患者42例以完全随机分组法随机分为A组(杜氟合剂强化麻醉组)和B组(DEX强化麻醉组),每组21例。A组给予杜氟合剂(盐酸哌替啶25mg+氟哌利多2.5mg),B组给予DEX,DEX以2ml
2、(200I.Lg)]J11人48rnl生理盐水中,以0.8pg/I【g的剂量以微量泵10min内缓慢静脉注射给予负荷量,继以0.4斗g-kg-I·h4持续泵入至手术前10min停用。于强化麻醉前(To)、强化麻醉后5(T。)、10(T2)、30min(T3),术毕(T4)记录收缩压(systolicbloodpressure,SBP)、舒张压(diastolicbloodpressure,DBP)、心率(heartrate,HR)及经皮血氧饱和度(transcutaIleousoxygensaturation,Sp02)、疼痛视觉模拟评分(visualanaloguescal
3、e,VAS)、Ramsay评分及相关副作用。结果B组于Tl、T2、T43个时间点VAS评分低于A组[0(3.5)VS3.5(3),0(1)VS2(2.75),0(1)VS2.5(3)](P0.05);两组组内各时间点SBP、DBP、HR变化有统计学意义(P<
4、0.01);组内各时间点SpO:比较差异无统计学意义(P>0.05);igi组间各指标各时间点比较差异无统计学意义(尸>0.05)。结论静脉泵注DEX具有较好的镇静、镇痛效果,安全性高,可作为臂丛麻醉阻滞不全时的强化麻醉药物选择。【关键词】右美托咪定;强化麻醉;臂丛;神经阻滞EffectofpotentiatedanesthesiaofdexmedetomidineinpatientswinlincompletebrachialplexusblockMIA0Wen4i.ZHANGYuan-xin,WANGDe-ming,WUChun-min,QuYan4iang,WENBao
5、-lei.DepartmentofAnesthesiology,MilitaryCenterofHandSurgery,NO401HospitalofPLA,Qing,‰266071,ChinaCorrespondingauthor:MIA0Wen4i,Emial:miaowenlil216@163.corn【Abstract】ObjectiveToevaluatetheeffectofpotentiatedanesthesiaofdexmedetomidine(DEX)whenbrachialplexusblockwereunsuccessful.Methods42pati
6、entswithincompletebrachialplexusblockwererandomlydividedinto2groups(groupAandgroupB,n=21).Sauteralgyl25mganddroperidol2.5mgwereusedingroupA,O.8斗s/kgofDEXwereusedingroupBwithin10minasabolus,and0.4斗g·kg。·h~ofDEXwereinfusedcontinuouslyuntiltheendoftheoperation.Systolicbloodpressure(SBP),diasto
7、licbloodpressure(DBP),heartrate(HR),transcutaneousoxygensaturation(Sp02),visualanaloguescale(VAS),Ramsayscoreandothersideeffectswererecordedbeforepotentiatedanesthesia(To)and5(T1),10(T2),30min(T3)afterpotentiatedanesthesiaandendofoperation(To).ResultsCom
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