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时间:2019-05-12
《电子射野影像系统对鼻咽癌调强放疗摆位误差的测量》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中国医科大学硕士学位论文电子射野影像系统对鼻咽癌调强放疗摆位误差的测量姓名:郭根燕申请学位级别:硕士专业:肿瘤学指导教师:刘晓岚20100301·中文结构式摘要·电子射野影像系统对鼻咽癌调强放疗摆位误差的测量目的分析鼻咽癌调强放射治疗(IMRT)的摆位误差情况,从而确定摆位扩边的大小。方法选取采用调强放疗的鼻咽癌患者15例,放射治疗过程中每位患者前3次治疗及之后每周拍摄电子射野验证片(正侧位),共拍摄194张。应用电子射野影像系统(EPID)将验证片与数字重建射野影像(DRR)配准,分别测定左、右、头、脚、腹、背(L、R、H
2、、F、A、P)六个方向的摆位误差。结果六个方向的摆位误差90.21%<2mm,98.63%<3mm,100%<5mm。总体系统误差L-0.6mm(士0.88s),R0.58mm(士1.02s),H0.08ram(+0.71s),F0.21ram(4-0.54s),A0.00ram(+1.12s),P0.00mm(+0.97s);随机误差的标准差分别为士0.55,-4-0.45,如.56,士0.52,士0.48,:tO.43ram;六个方向的摆位扩边值分别为2.59,2.85,2.17,1.72,3.15,2.72mm。结论在
3、EPID系统下进行实时测量和纠正摆位误差,可降低系统误差和随机误差,提高摆位精度。关键词鼻咽癌;调强放疗;摆位误差;电子射野影像系统·英文结构式摘要·ElectronicportalimagingdeviceinsetupverificationinintensitymodulatedradiationtherapyfornasopharyngealcarcinomaobjfectiveToinvestigatethesetupverificationusingelectronicportalimagingfornasoph
4、aryngealcarcinomaintensitymodulatedradiation(IMRT).Methods15patientswereenrolledinstudy.Electronicportalimages(EPI)wereacquiredinfirst3daysandonceeveryweekduringtheradiationcourseandatotal194anteriororlateralisocentricEPlwerecomparedtodigitallyreconstructedradiogra
5、ph(DRR)usingelectronicportalimagingdevice(EPID),sixdirectional(1eft—L,right-R,head-H,foot-F,anterior-A,post-P)setuperrorscanbeacquired.ResultAbout90.21%ofalltranslationalsetuperrorswere<_2mm,98.63%<3mm,and100%<5ram.Theoverallsystematicerrorwas一0.6ram(+0.88s)inL-dir
6、ection,O.58rain(士1.02s),inR—direction,0.08mm(士O.71s),inH-direction0.21ram(士O.54s)inF-direction,0.00mill(士1.12S)inA—direction,0.00ram(士0.97s)inP—direction.ThecorrespondingSoftherandomerrorswere士O.55,士o.45,:tO.56,士O.52,圭O.48,士O.43mm.TheestimatedmarginsrequiredforCTV—
7、PTVwerecalculatedaccordingtothevanHerkformulawas2.59,2.85,2.17,1.72,3.15,2.72mm,respectively.ConclusionOn—lineinvestigationandcorrectionofsetupG丑TorusingEPIDcallreducesystematicell'Orandrandomerrorandthenimprovesetupprecision.2Keywordsnasopharyngcalcarcinoma;intens
8、itymodulatedradiationtherapy(IMRT);setuperror;electronicportalimagingdevice(EPID)3·英文缩略语·4中国医科大学研究生学位论文独创性声明本人申明所呈交的学位论文是我本人在导师指导下进行的研究工作及取得的研究成果
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