多排螺旋ct冠状动脉成像在左主干病变诊断中的应用

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1、授予单位代码10089学号或申请号13204HebeiMedicalUniversity硕士学位论文在职科学学位多排螺旋CT冠状动脉成像在左主干病变诊断中的应用学位申请人：郭震导师：徐泽升教授专业：内科学二级学院：沧州市中心医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下，由本人独立完成。本学位论文研究所获得的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文,第一署名为单位河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。

2、否则，承担相应法律责任。研究生签名导师签章_学院领•章：日河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果,除了文中特别加以标注和致谢等内容外,文中不包含其他人已经发表或撰写的研究成果,指导教师对此进行了审定。本论文由本人独立撰写,文责自负。目录中文摘要·············································································1英文摘要·······························································

3、··············3英文缩写·············································································5研究论文多排螺旋CT冠状动脉成像在左主干病变诊断中的应用前言·············································································6资料与方法····································································7结果··········

4、···································································9附图·············································································13附表·············································································14讨论···························································

5、··················18结论·············································································22参考文献·······································································23综述多排螺旋CT冠状动脉成像在左主干病变诊治中的应用···········26致谢········································································

6、···········33个人简历·············································································34中文摘要多排螺旋CT冠状动脉成像在左主干病变诊断中的应用摘要目的：通过多排螺旋CT（MSCT）冠状动脉血管成像（MSCTA）与冠状动脉造影（CAG）在诊断左主干病变（LMCA）方面的对比研究，探讨无创性检查MSCTA在LMCA诊疗及对冠状动脉斑块定性分析的价值。方法：入选2013年1月至2014年12月就诊于沧州市中心医院心内科，临床诊断为冠状动脉粥样硬化性心脏病，并在1周内同时行MSC

7、TA、CAG检查的患者。共入选301例，其中男性173例，女性128例，平均年龄（60.7+11.8）岁。将LMCA病变按部位分为近端病变（病变位于左主干开口3mm内）、中段病变、末端病变（病变位于左主干末端分叉前3mm内），以CAG为标准，比较MSCTA与CAG在诊断LMCA近端病变、中段病变、远端病变的敏感性、特异性、阳性预测值、阴性预测值和可靠性；观察冠状动脉斑块性质与冠状动脉管腔狭窄程度两者是否存在关系；观察MSCTA在诊断冠状动脉病变不同狭窄程度的准确性时是否存在差异；对比MSCTA在诊断LM