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ID:33007629
大小:2.11 MB
页数:41页
时间:2019-02-19
《改变非小细胞肺癌适形放疗纵隔照射靶体积的对照分析》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、patients)beforeRRT,thesepatientshadn’treceivedPNIofmediastinallymphnodedrainagewherehadn’tmetastasisbelievedbyCTcombinedwithPET.PatientswithoutPET(non—PETpatients)hadreceivedPNIaccordingtoconventionalmethod.ThedifferenceofCTVbetweentwogroups、,VaS133.31士34.26cm3.Allpa
2、tientsintwogroupsweretreatedwiththeSOATIemethod.Peripherallesionsinlungweretreatedwithlowfmctionatedradiotherapy(LFRT),以8Gyineveryonefraction,3fractionsinaweek,andatotaldoseof56~60Gyweredeliveredin7~10fractionswithin2~3weeks.LesionsinhilaandmediastinHalweretreatedwit
3、hAFRT,3Gyineveryonefraction,5fractionsinaweek,apreventivedoseof42~45Gyweredeliveredin14~15fractionswithin3weeks,andaradicalradiationdoseof60~63Gyweregivenin20-21fractionswithin4~5weeks.Twoyearssurvivalrate.10calcontroloflymphnodedrainageandirradiationinjuryoflungando
4、esophagusbetweenthetwogroupshadbeencompared.Statisticalanalysis:AlldatawereanalysedbythesoftwarepackagesofSPSS10.OResults:Thefirstpart:Twoyearssurvivalratesofpatientsintwopost—operationradiotherapygroupswere55.2%and62.5%respectivelyrP=0.59).Thelocalregionalrelapserat
5、esandtherecnrrenceoutofCTVwere13.8%.3.4%forgroupAand16.7%.8.3%forgroupBrespectively(P=-iandP-=0.571).TherewerenodecreaseofthelocalcontrolingroupBbythereductionofCTV.Theradiationpneumoniaandlungfibrosisrateswere6.9%.62.1%forgroupAand0.58.3%forgroupBrespectively(e=-0.4
6、59andP=0.782).Theradiationoesophagitisandoesophagusstricturerateswere37.9%.6.9%forgroupAand12.5%.4.2%forgroupBrespectively(P=-0.039andP=-1).Theincidenceofradiationoesc。phagitisingroupBweredecreasedsignificantly.Thesecondpart:TwoyearssurvivalrateofRRTwas53.1%forPETpat
7、ientsand43,2%fornon-PETpatientsrespectivelyrP=0.357).Thedistantmetastasisratewas25.0%forPETpatientsand52.3%fornon—PETpatients5respectivelyfP=0.0174).Thelocalregionalrelapseratesofthehilaandmediastinunawere21.9%forPETpatientsand25.0%fornon—PETpatientsrespectively(e=-0
8、.752).TherecurrenceoutofCTVwere6.3%forPETpatientsand4.5%fornon—PETpatientsrP=O.831).Theradiationoesophagisandoesophagusstricturerat
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