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1、马来酸曲美布汀联合沙棘干乳剂治疗功能性消化不良的临床效果评价张京(保定市第二医院河北保定071000)【摘要】R的:探讨马來酸曲美布汀联合沙棘干乳剂治疗功能性消化不良的临床效果。方法:本次选取资料为2014年3月至2015年3月来我院消化内科门诊收治的90例患者,根据随机分组法将患者分为对照组45例,观察组45例。对照组患者给予马来酸曲美布汀门服,观察组患者给予门服马來酸曲美布汀的同时给予沙棘干乳剂,两组患者均治疗2周。根据两组患者的消化不良评分情况对两组进行疗效判定。结果:经过2周的治疗,观察组患者总有
2、效率为91.1%,对照组患者总有效率为48.9%,对照组患者的总有效率明显低于观察组患者的总有效率,P<0.05统计学差异显著;对照组患者无效率明显高于观察组患者的总有效率,P<0.05统计学差异显著。结论:马来酸曲美布汀联合沙棘干乳剂治疗功能性消化不良的治疗效果优于单纯使用马来酸曲美布汀的治疗效果,且临床不良反应未见,值得在临床使用。【关键词】马來酸曲美布汀;沙棘干乳剂;功能性消化不良;临床效果【中图分类号】R453【文献标识码】A【文章编号】1007-8231(2015)22-0043-0
3、2MalaisuanQumeibutingjointseabuckthorndryemulsioninthetreatmentoffunctionaldyspepsiaclinicaleffectassessmentZhangjing.Thesecondhospitalofbaoding,Hebeibaoding071000,China[Abstract]ObjectiveTostudythemaleicacidjointtrimebutineseabuckthorndryemulsionsclinica
4、leffectforthetreatmentoffunctionaldyspepsia.MethodsThedataofMarch2014toMarch2014of90patientsadmittedintoourdigestiveinternalmedicineoutpatientservice,accordingtotherandomgroupingmethoddividedthepatientsintocontrolgroup45cases,observationgroup45cases.Contr
5、olgrouppatientsgivemaleicacidtrimebutineoral,observationgrouppatientsgiveoralmaleicacidoftrimebutinegiveseabuckthorndryemulsionatthesametime,twogroupsofpatientsweretreatedfor2weeks.Accordingtothesituationoftwogroupsofpatientswithdyspepsiascoreoftwogroupso
6、fcurativeeffect.ResultsAfter2weeksoftreatment,theobservationgroupofpatientswiththetotaleffectiveratewas91.1%,controlgrouptotaleffectiveratewas48.9%,controlgrouptotaleffectiverateinpatientswithsignificantlylowerthantheobservationgroupofpatientswithtotaleff
7、ectiverate,P<0.05,statisticallysignificantdifference;Controlpatientswithoutefficiencyissignificantlyhigherthantheobservationgroupofpatientswithtotaleffectiverate,P<0.05,statisticallysignificant.ConclusionMaleicacidjointtrimebutineseabuckthorndryemul
8、sioninthetreatmentoffunctionaldyspepsiatreatmenteffectisbetterthanthatofpureusingmaleicacidtreatmenteffectoftrimebutine,andclinicaladversereactionsdidnotsee,isworthinclinicaluse.【Keywords】Maleicacidtrimebutine;Seabu