欢迎来到天天文库
浏览记录
ID:20723425
大小:69.00 KB
页数:13页
时间:2018-10-15
《40例帕金森病患者非运动症状的时序性分析》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、[摘要]目的通过对帕金森病患者各种非运动症状发生前后的时序进行分析,探讨帕金森病患者非运动症状出现早晚的临床特征。方法对40例帕金森病患者进行“帕金森病常见的非运动症状问卷”结合部分常见的运动症状进行调查,并结合性别、病程等可能的影响因素对非运动症状发生前后时序进行排列评估。结果在40例帕金森病患者中,味觉或嗅觉减退或丧失是最先开始出现的症状,在确诊帕金森病前就开始出现(平均发病前1.2个月出现),且发生率高[57.5%(23/40)];其次出现时间较早的症状依次是皮炎、感到难以入睡或失眠、因为头晕或失去知觉而摔倒,这3个症状平均在确诊后半年内出现,发生率相对较低[分别为12.5%(5
2、/40),27.5%(11/40),5.0%(2/40)];较晚出现的症状有幻觉(看到或听到一些你知道或者被告知并不存在的事情)、发声困难或异常、有不明原因的疼痛(并非已知原因导致如关节炎)、流涎、色觉异常,这5个症状平均在确诊发病6年以后才出现。结论帕金森病患者的非运动症状中,首先出现的是味觉或嗅觉的减退,且早于运动症状;其次是皮炎,睡眠障碍,头晕,较晚出现的是幻觉、发声困难或异常、不明原因的关节疼痛、流涎、色觉异常。[关键词]帕金森病;非运动症状;时序性;发生率[中图分类号]R742.5[文献标识码]B[文章编号]1673-9701(2017)08-0094-04[Abstract
3、]ObjectiveToinvestigatetheclinicalcharacteristicsofnon-motorsymptomsonsetinpatientswithParkinson'sdiseasebyanalyzingthetimingofvariousnon-motorsymptomsinpatientswithParkinson'sdisease.Methods40patientswithParkinson'sdiseasewereinvestigated"Parkinson'sdiseasecommonnon-motorsymptomquestionnaire1'c
4、ombinedwithsomecommonsymptomsofmotor.Andthetimingofnon-motorsymptomswasassessedwiththecombinationofsex,durationandotherpossiblefactors.ResultsIn40patientswithParkinson'sdisease,tasteorsmelldiminishmentorlosswerethefirstsymptomstoappear,whichhappenedbeforethediagnosisofParkinson'sdisease(1.2month
5、sbeforetheonsetonaverage)andhadahighincidence[57.5%(23/40)].Thefollowingsymptomsweredermatitis,feelinghardtofallasleeporinsomnia,fallingdownbecauseofdizzinessorlossofconsciousness,andthethreesymptomsoccursinthesixmonthsaftertheinitialdiagnosisonaveragewithrelativelylowincidence[12.5%(5/40),27.5%
6、(11/40),5.0%(2/40)]•Symptomsappearinglaterwereillusionstoseeorhearsomethingyouknoworaretoldthatdoesnotexist,dysphoniaorabnormality,andunexplainedpainwhichisnotknowntocausearthritis,salivationandabnormalcolorvision.Theabovesymptomswereseenonlyafter6yearsofdiagnosis.ConclusionAmongthenon-motorsymp
7、tomsinParkinson'sdiseasepatients,thefirstappearanceisthetasteorsmellofdecline,whichisearlierthanthemovementsymptoms,followedbydermatitis,sleepdisorders,dizziness.Andhallucinations,dysphoniaorabnormalities,unexplainedjointpai
此文档下载收益归作者所有