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1、UrinaryObstruction&BenignProstaticHyperplasia(BPH)XiaoHuang,MD;PhDDepartmentofUrology,1stAffiliatedHospitalofZhejiangUniversity,SchoolofMedicineUrinaryObstructionUrinaryTractAnatomyUrinaryObstructionReasonofUrinaryObstructionHydronephrosisUrinaryTractAnatomyUrinaryObstructionReasonofUrinary
2、ObstructionObstructionReasonClassificationDynamicandstructuralCongenitalandaquiredPopulationsChild:congenitalAdults:stone,injury,tumor,TBWomen:pelvicdiseaseOldmen:BPHLocationsKidney:calculus,tumor,infection,TB,UPJstricture,congenitaldeformityUreter:stone,tumor,iatrogenicinjury,ureteritis,TB
3、,MetastaticcarcinomaBladder:BPH,bladderneckcontracture,tumor,calculus,NeurogenicbladderUrethral:urethralstricture,Phimosis,CongenitalPosteriorurethralvalve,stone.HydronephrosisWhatishydronephrosis?Hydronephrosisisa"stretching"ordilationoftheinside,orcollectingpart,ofthekidney.Itoftenresults
4、fromablockageintheureterwhereitjoinsthekidneythatpreventsurinefromdrainingintothebladder.Urineistrappedinthekidneyandcausesittostretch.Hydronephrosismayalsobeduetoabnormalbackwashor"reflux"ofurineintothebladder.DegreesofHydronephrosisKidneyfunction:MinimallyaffectedcompensationdamageBenignP
5、rostaticHyperplasia(BPH)ObjectivesWhatisaBPHHowtoapproachapatientwithLUTS(lowerurinarytractsymptoms)TreatmentofBPHOutline1.DefinitionofBPH2.AnatomyandPhysiology3.MicroscopicAppearance4.PrevalenceofBPH5.Etiology6.NaturalHistoryofBPH7.LUTS8.ApproachtoapatientwithBPH9.IPSS10.DifferentialDiagno
6、sis11.ManagementofBPH12.TreatmentofBPH1.DefinitionBPHisanonmalignantenlargementoftheprostateglandcausedbycellularhyperplasiaofbothglandularandstromalelementsthatleadstotroublesomelowerurinarytractsymptoms(LUTS)insomemenItisthemostcommonbenigntumorinmenandisnotaprecancerouscondition2.Anatomy
7、andphysiologyTheprostateisacompoundtubuloalveolarexocrineglandofthemalemammalianreproductivesystemFunctionistostoreandsecreteaclear,slightlyalkalinefluidthatconstitutes10-30%ofthevolumeoftheseminalfluidthatalongwiththespermatozoa,constitutessemenSecretis