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1、肾活检1542例临床病理资料分析作者：杜娟丽，王汉民，于艳，连耀国，陈威，张静，刘彦仿【关键词】肾脏疾病；肾;活组织检查；病理类型；回顾性分析Analysisonclinicopathologicaldataof1542casesundergoingrenalbiopsy【Abstract】AIM:Toinvestigatetherelationbetweenrenalpathologicalcategoryandclinicalfeaturesbyanalyzingtheclinicopathologicaldatein154caseshavingunderwentrenalb
2、iopsy.METHODS:PathologicalclassificationsweremadeaccordingtotheWHOcriteriaof198forrenalpathologyorthemodifiedWHOcriteriaof199andtheclinicaldata,laboratoryresults,lightmicroscopy,immunefluorescenceandelectronmicroscopybyapanelofpathologistsandnephrologistsinroutineclinicalpathologicalrounds.RE
3、SULTS:Theaverageageatrenalbiopsy±15.(6-63)yearsoldin154patientswithrenaldiseases,andtheratioofmaletofemalewas∶1.Primaryglomerulardiseases(PGD)accounted%,secondaryglomerulonephritis(SGN)%,andendstagerenaldisease(ESRD)%.ThePGDindescendingorderofincidence,weremesangialproliferativeglomerulonephr
4、itis(MsPGN,%),focalsegmentalglomerulosclerosis(FSGS,%)andIgAnephropathy(%).TheSGNindescendingorderofincidence,werelupusnephritis(%),purpuranephritis(%)andhepatitisBvirusassociatednephritis(HBVGN,%).Thechronicrenalfailureindescendingorderofincidence,wereIgAnephropathy(%),proliferativesclerosin
5、gglomerulonephritis(PSGN,%)andFSGS(%).CONCLUSION:Inourarea,renaldiseasesoftenhappeninyoungpeople.PGDisadominatingtypeinwhichMsPGNisthemostcommon.IntheSGN,lupusnephritisisdominant.ThemajorpathologicalcategoriesofthecausesofchronicrenalfailureareIgAnephropathyandPSGN.【Keywords】renaldisease;rena
6、l;biopsy;pathologicalcategory;retrospectiveanalysis【摘要】目的：回顾性分析1542例因肾脏疾病行经皮肾活检患者的病理类型和临床资料并探讨二者之间的联系.方法：参照WHO肾小球疾病组织学分型方案，结合临床资料、实验室检查结果、光镜、免疫病理及电镜的改变特点，提出初步诊断，最后与临床医师共同讨论确定诊断.结果：患者行肾活检时平均年龄±岁，男女之比为∶1.原发性肾小球疾病占首位，继发性肾小球疾病占%，终末期肾病占%.原发性肾小球疾病的病理类型中最多见为系膜增生性肾小球肾炎，其次为局灶节段性肾小球硬化症和IgA肾病.继发性肾小球疾病以狼
7、疮肾炎居首位，其次为紫癜性肾炎和乙肝相关性肾炎.引起慢性肾功能不全的病理类型依次为IgA肾病、增生硬化性肾小球肾炎和局灶节段肾小球硬化症.结论：本地区肾脏疾病多见于青壮年，以原发性肾脏疾病最常见，其中系膜增生性肾小球肾炎是最多见的病理类型.继发性肾小球疾病以狼疮肾炎最常见.引起慢性肾功能不全最常见的病理类型为IgA肾病和增生硬化性肾小球肾炎.【关键词】肾脏疾病；肾;活组织检查；病理类型；回顾性分析 0引言肾脏疾病是我国的常见病、多发病，也是接受透析或肾移植的最直接原因.因此，尽早
