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1、儿童紫癜性肾炎41例从“毒”论治研究作者:赵智强,耿珊珊,孙轶秋,郁晓维,韩新民【摘要】目的从“毒”探讨儿童紫癜性肾炎的发病机理及治疗,以探寻新的中医病因病机及治疗学理论。方法回顾江苏省中医院儿科2002-2006年41例儿童紫癜性肾炎住院病例,观察“毒”的临床表现,着重从处方药物组成着手,探讨相关治法。结果本病具有“毒”的致病特点与临床表现,“毒”的针对性治疗包括解毒(凉血化瘀解毒、活血解毒、清热解毒、祛风解毒、除湿解毒)、排毒(利尿泄毒、通腑泄浊)、抗毒(益气、养阴),其配伍多以凉血化瘀解毒为核心。结论“毒”是本病的重要致病因素之一,从“毒”论治有重要的临床价值。【关
2、键词】儿童紫癜性肾炎;毒邪;解毒;排毒;抗毒【Abstract】ObjectiveTostudythepathogenesisandtreatmentofHenoch-SchonleinpurpuraofchildrenfromtoxinandlookfornewtheoryofpathogenyandtherapeuticsinChinesemedicine.Itcanmaketreatmentbytheoryoftoxinbecomeanewwaytoimprovecurativeeffect,shortencourseofthediseaseandreducerec
3、rudescence.MethodsWecollectedthepatientswhowereinhospitalofTCMinJiangsuProvincefrom2002to200612andestablishedstudyingstandards.Weobservedtherelationbetweensymptomandtoxininordertostudypathogenesisoftoxin.Weextractedprescriptionandsummedupdrugsincommonuseandrepresentativetherapeuticsofthat
4、.Weanalyzedtheinternalprincipiumofthetherapeuticsinordertoseekapplyingofdetoxifcation,drainingtoxinandresistingtoxin.ResultsThediseasehasthecharactersandsymptomsoftoxin,andtoxinrunthoughallthecoursesofit.Toxinconsistsofinternaltoxinandexternaltoxin.Externaltoxinincludessix-eviltoxin,foodt
5、oxin,insecttoxinandmedicinetoxin.Intertoxinincludesblood-blacktoxin,wettoxinandheattoxin.Toxinusuallycausesthediseasealongwithwind,heat,blood-blackandwet.Thespecialtherapeuticsoftoxinincludesdetoxifcation,drainingtoxinandresistingtoxin.Thesemethodsarecoolingbloodanddetoxifcation,clearingh
6、eatanddetoxifcation,dispellingwindanddetoxification,diuresisanddetoxifcation.Weusuallyusethreeorfourofthem,sometimesusetwoofthem.Theircoreofmatchusuallyiscoolingbloodanddetoxifcation.Furthermore,weusealongwithothertreatmentaccordingtostate,locationoftheillnessandconstitutionofpatients.Con
7、clusionToxinisoneofpathogenyfactors,wecanstudythepathogenesisfromtoxin,inordertoestablishthenew12theoryofpathogeny,guidetreatmentandimprovecurativeeffect.【Keywords】Henoch-Schonleinpurpuraofchildren;toxin;detoxifcation;drainingtoxin;resistingtoxin紫癜性肾炎是过敏性紫癜最严重的一种并发症