中医药提高晚期非小细胞肺癌患者生存质量的临床观察

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1、中医药提高晚期非小细胞肺癌患者生存质量的临床观察坚垦中西医缝合杂志2006年5月第26卷第5期CJITWM,May2006,Vo1.26,No.5临床论着中医药提高晚期非小细胞肺癌患者生存质量的临床观察-389?林丽珠周岱翰郑心婷摘要目的观察中医药疗法提高Ⅲ,Ⅳ期非小细胞肺癌(NSCLC)患者生存质量的作用,确立中医药治疗晚期NSCLC的治疗方案.方法将6所医院294例NSCLC患者随机分为中医组(99例,中医辨病和辨证治疗),西医组(92例,化疗)和中西医组(103例,中医辨病辨证治疗联合化疗).采用肺癌治疗功能评价表(FACT

2、.L量表)分别对身体状况,社会家庭状况,与医生关系,情绪状况,功能状况和附加的关注状况等6个板块进行调查分析.结果社会家庭状况,与医生关系两板块各疗程结束后与治疗前比较差异无显着性(P>005),身体状况板块的改善以中医组最优(P<0.05),而情绪板块,功能板块的改善均以中西医组最优(P<0.05).结论中医药对于化疗的毒副反应有一定的拮抗作用,在一定程度上维护了患者的生存质量.关键词中医药疗法;中西医结合疗法;非小细胞肺癌;生存质量EffectofTraditionalChineseMedicineinImp

3、rovingQualityofLifeofPatientswithNon-smallCellLungCancerinLateStageLINLi—zhu,ZHOUDai—han,andZHENGXin—tingTheSecondDepartmentofOncology,TheFirstHospitalAffiliatedtoGuangzhouUniversityofTraditionalChineseMedicine.Guangzhou(510405)AbstractObjectiveToobservetheeffectoftra

4、ditionalChinesemedicine(TCM)inimprovingqualityoflifeofpatientswithnon—smallcelllungcancer(NSCLC)inⅢorⅣstage,forestablishingTCMtherapeuticregimenonlateNSCLC.MethodsAtotalof294patientsin6hospitalswererandomlyassignedintothreegroups,99intheTCMgrouptreatedwithTCMaccording

5、todiseaseandsyndromedifferentiation,92treatedwithchemotherapyinthewesterngroupand103treatedwithcombinedtherapyofTCMandchemotherapyintheintegrativegroup.Sixitems,includingphysicalstatus,social/familystatus,intercoursewithphysicians,e—motionalstatus,functionalstatusanda

6、dditionalconcerningstatus,wereinvestigatedandanalyzedbyusingFunctionalAssessmentofCancerTherapy—lung(FACT—L).ResultsThescoresofsocial/familystatusandin—tercoursewithphysicianswereinsignificantlydifferentinallthreegroupsbeforeandaftertreatment(P>0.05).Theimprovement

7、ofphysicalstatusintheTCMgroup,andthatofemotionalstatus,functionalstatusandadditionalconcernedstatusintheintegrativemedicinegroupweresuperiortothoseintheothergroups(P<0.05).ConclusionTCMhascertainantagonisticeffectontheadversereactionofchemotherapy,anditcanimproveth

8、equalityoflifeofpatientstocertainextent.KeywordstraditionalChinesemedicinaltherapy;therapyofintegrativemedicine;non—smallcel