欢迎来到天天文库
浏览记录
ID:54924718
大小:544.94 KB
页数:9页
时间:2020-05-04
《抗病毒治疗对慢乙肝相关致癌因素的干预研究-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、现代生物医学进展www.shengwuyixue.comProgressinModernBiome~cineVoL14NOg.0JUL2014·3909·doi:10.132418.cnki.pmb.2014.20.029TheStudyofInterventionOfAntiviralTherapytoChronicHepatitisB.RelatedCarcinogensCHENFe,WANGZhe-linge,GAOR砸,L1UZhong-jingeflQingdaoUniversRy;Qing
2、dao,Shandong,266021,China;2QingdaoInfectiousDiseasesHospital,Qingdao,Shandong,266033,C盈血】a】ABSTRACTObjective:Toinvestigatetheinterventionofantiviralther~yontheriskfactorsofchronichepatitisB-relatedhepatoc-ellularcarcinoma.Methods:249hospitalizedcasesofh
3、epatocellularcarcinomainQingdaoInfectiousDiseasesHospitalfromFebruary2010toJune2012wereretrospectivelyanalyzed.Therelevantdatarecordedonthequestionnairepreparedbytheunifiedwasusedtocomparethedistributionofvariousfactorsbetweenantiviraltreatmentgroupandn
4、o—antiviraltreatmentgroup.Results:ThediferencesoftimeofHBVinfectionandthatofcirrhosisbeforediagnosedwithHCC,andHBVDNAlevelbetweenantiviraltreatmentgroupandno-antiviraltreatmentgroupwerestatisticallysignificant,P<0.05;HBVinfectionpatterns,AFP,CEAhadnosig
5、nificantdiferencesbetweenthetwogroups.Diferencesofrelatedindicatorsofliverfunctionwerestatisticallysignificant.Conclusions:AntiviralthempycouldsignificantlyreducethepercentageofthecarcinogenicfactorsassociatedwithchronichepatitisBinpatients,anditcanefec
6、tivelyinhibitthereplicationofHBVDNA,whichmaybereducetheincidenceofHBV-relatedHCC.Keywords:Hepatocellularcarcinoma;ChronichepatitisB:Riskfactors;AntiviraltherapyChineseLibraryClassifieation(CLC):R512.6,R735.7Documentcode:AArticleID:1673-6273(2014)20-3909
7、·-05metabolicandotherreasonscirhosis,thecancerofotherpartsandIntroductionmetastaticlivercanceralsowereremoved.Thesubjectsaredivid-ChronichepatitisBvirus(HBV)infectionisthemainreasonedintoantiviraltreatmentgroupandno-antiviraltreatmentgroupofhepatocellul
8、arcarcinoma(HCC)inChina.ThemajorityofHCCbasedthatiftheytooktheoralnucleosideantiviraldrugs.isevolvedfromcirrhosisafterHBVinfectionB21.andtherelevant1.2ContentsoftheobservationinformationshowsthathighHBVDNAlevelistheabsoluteriskAl
此文档下载收益归作者所有