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时间:2020-04-24
《冠心病患者血清胆红素、超敏C反应蛋白及同型半胱氨酸的表达及临床意义-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中国医药导报2014年5月第l1卷第13期·临床研究·冠心病患者血清胆红素、超敏c反应蛋白及同型半胱氨酸的表达及临床意义程昌霞周建华曹武湖北医药学院附属太和医院心内科,湖北十堰442000【摘要】目的探讨冠心病(CHD)患者血清胆红素、超敏C反应蛋白(hs—CRP)和同型半胱氨酸(Hcy)水平与冠心病之间的关系。方法选择2011年1月~2013年10月湖北医药学院附属太和医院确诊的CHD患者86例为CHD组.另外选择50例体检健康者作为对照组。观察组按病变支数分为单支病变和多支病变,其中单支病变组52例,多支病变组34例。测定胆红素、hs—CRP和Hcy的含量。结果CHD组
2、hs—CRP[(16.04~5.19)mg/L】及Hcyf(27.42~5.14)Ixmol/L】水平均显著高于对照组[(1.57~1.53)mg/L、(7.49~1.56)I~mol/L】,差异有统计学意义(P<0.05);多支病变组血hs—CRP[(17.05~5.25)mg/L]、Hcy[(36.10~3.25)mol/L]明显高于单支病变组[(8.16~3.17)mg/L、(22.08~4.92)Ixmol/L]和对照组『(1.57~1.53)mg/L、(7.49~1.56)~mol/L],差异有统计学意义(P<0.05)。CHD组总胆红素水平『(10.12~3.2
3、1)I~mo]/L]显著低于对照组【(14.02~5.11)Ixmol/L],差异有统计学意义(P4、039-03Clinicalsignificanceofthelevelsofserumbilirubin,highsensitivityC—reactiveproteinandhomocysteineinpatientswithcoronaryheartdiseaseCHENGChangxiaZHOUJianhuaCA0WuDepartmentofCardiology,theAffiliatedTaiheHospitalofHubeiMedicalCollege,HubeiProvince,Shiyan442000,China【Abstract】0bjectiveToex5、ploretherelationshipbetweentheserumbilirubin,highsensitivityC—reactiveprotein(hs—CRP)andhomocysteinelevelsofcoronaryheartdiseasepatientsandcoronaryheartdisease(CHD).Methods86casesofpatientsdiagnosedCHDintheAfiliatedTaiheHospitalofHubeiMedicalCollegefromJanuary2011toOctober2013wereselecteda6、stheCHDgroup,50casesofhealthysubjectswereselectedasthecontrolgroup.PatientsinCHDgroupweredividedintosinglevesselsubgroup(52cases)andmultivesselssubgroup(34cases)accordingtothenun—berofdiseasedvessels.Thelevelsofbilirubin.hs—CRPandhomocysteineweremeasured.ResultsThelevelsofserumhs—CRPandHcy7、inCHDgroup【(16.04~5.19)mg/L,(27.42~5.14)Ixmol/L]weresignificantlyhigherthanthoseinthecontrolgroup[(1.57~1.53)mg/L,(7.49~1.56)Ixmol/L],thedifferencewerestatisticallysignificant(尸<0.05).Thelevelsofserumhs—CRPandHcyinthemultivesselssubgroup[(17.05~5.25)mg/L,(36.1
4、039-03Clinicalsignificanceofthelevelsofserumbilirubin,highsensitivityC—reactiveproteinandhomocysteineinpatientswithcoronaryheartdiseaseCHENGChangxiaZHOUJianhuaCA0WuDepartmentofCardiology,theAffiliatedTaiheHospitalofHubeiMedicalCollege,HubeiProvince,Shiyan442000,China【Abstract】0bjectiveToex
5、ploretherelationshipbetweentheserumbilirubin,highsensitivityC—reactiveprotein(hs—CRP)andhomocysteinelevelsofcoronaryheartdiseasepatientsandcoronaryheartdisease(CHD).Methods86casesofpatientsdiagnosedCHDintheAfiliatedTaiheHospitalofHubeiMedicalCollegefromJanuary2011toOctober2013wereselecteda
6、stheCHDgroup,50casesofhealthysubjectswereselectedasthecontrolgroup.PatientsinCHDgroupweredividedintosinglevesselsubgroup(52cases)andmultivesselssubgroup(34cases)accordingtothenun—berofdiseasedvessels.Thelevelsofbilirubin.hs—CRPandhomocysteineweremeasured.ResultsThelevelsofserumhs—CRPandHcy
7、inCHDgroup【(16.04~5.19)mg/L,(27.42~5.14)Ixmol/L]weresignificantlyhigherthanthoseinthecontrolgroup[(1.57~1.53)mg/L,(7.49~1.56)Ixmol/L],thedifferencewerestatisticallysignificant(尸<0.05).Thelevelsofserumhs—CRPandHcyinthemultivesselssubgroup[(17.05~5.25)mg/L,(36.1
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