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时间:2017-12-07
《芪棱汤对脑缺血再灌注大鼠脑微血管pecam-1表达的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、脑高级功能具有重塑性191。但是本次实验由于经费等多方面不足以f4】LeeCD,FolsomAR,BlairSN.Physicalactivityandstrokerisk:ametaanaly-致未进行疗效的长期观察,对其远期对于患者的生存质量及心理效se.Stroke,2003,34:2475—2481.应干预认识尚不明朗。[5】王刚,崔丽华,郭怡,等.脑卒中后抑郁的发生率及相关因素明.中国康复医学杂志,1998,13(5):216—217.[6】勾丽洁,许士奇.脑卒中后抑郁的临床研究进展[J1.中国康复医学杂志,参考文献:2007
2、,22(9):857—860.【11全国第四届脑血管会议。各脑血管诊断要点及脑卒中患者f临床神经功能缺【7l高红,陈静.脑卒中后发生抑郁的相关因素fJ】.黑龙江医学,2002,26(12):损程度评分标准(1995)叫.中华神经科杂志,1996,29,379.930.【2】GarrattAM,RutaDA,Abda~aMI,eta1.TheSF一36healthsurveyques6on—[8】赖红梅,万平,刘正云.有氧运动训练对大鼠下丘脑、垂体IL-113mRNA、IL-naire:Anoutcomemeasuresuitablefo
3、rroutineusewithintheNHS阴.British6mRNA的影响【J1.中国康复医学杂志,2007,22(6):693--695.MedicalJ0umal。1993,306:1440.[9]JohanssonBB.BrainplasticityandstrokerehabilitationL刀.Stroke,2000,31[3】张敬悬。李星宝,翁正.自知力与治疗态度问卷的临床试用【J】.山东精神医(1):223—230.学1994。4:10编辑,贺丽芪棱汤对脑缺血再灌注大鼠脑微血管PECAM-1表达的影响周荣峰(广东省
4、深圳市宝安区石岩人民医院,广东深圳518108)摘要:目的研究芪棱汤对脑缺血再灌注大鼠脑微血管PECAM-1表达的影响。方法将大鼠随机分为假手术组、模型组、对照组、治疗纽。采用颈内动脉线栓法复制大鼠脑缺血再灌注(MCAo/Repesion)模型。在再灌注不同时点采用免疫组织化学法测PECAM一1。结果假手术组极,5-PECAM-1表达;各相应再灌注时间点,治疗组及对照组比模型组的PECAM-I表达明显减少(P5、:脑缺血再灌注损伤;芪棱汤;血小板内皮细胞粘附分子一1EfectoftheExpressionofPECAM-1forQileng-decotiononBrainafterCerebralIschemiaPeperfusionRatZHOURong-feng(BaoanDistrict,ShiyanPeople'sHospital,Shenzhen518108,China)Abstract:0bjectiveTostudytheeffectoftheexpressionofPECAM-1inQileng-decoctiononbrain6、aftercerebralischemiareperfusionrat.MethodsTheratswererandomlydividedinto4groupsincludingthesham-operationgroup,theMCAO(MiddleCerebralArteryOcclusion)group,thecontrolgroupandthetreatmentgroup.theMCAOmodelw删establishedwithmethodofinternalcarotidarteryocclusionbysuture.PEC7、AM一1WaSobservedwithimmunohistochemistrymethodatdifferentreperfusiontime.ResultsTherewerefcwPECAM-1positiveinthesham—operatinggroup,theexpressionofPECAM-1inthetreatmentgroupandthecontrolgroupwerelowerthanthatintheMACOgroupatdiferentreperfusiontime.(P<0.O1),andthediference8、betweenthetreatmentgroupandthecontrolgroupwassignificant(P
5、:脑缺血再灌注损伤;芪棱汤;血小板内皮细胞粘附分子一1EfectoftheExpressionofPECAM-1forQileng-decotiononBrainafterCerebralIschemiaPeperfusionRatZHOURong-feng(BaoanDistrict,ShiyanPeople'sHospital,Shenzhen518108,China)Abstract:0bjectiveTostudytheeffectoftheexpressionofPECAM-1inQileng-decoctiononbrain
6、aftercerebralischemiareperfusionrat.MethodsTheratswererandomlydividedinto4groupsincludingthesham-operationgroup,theMCAO(MiddleCerebralArteryOcclusion)group,thecontrolgroupandthetreatmentgroup.theMCAOmodelw删establishedwithmethodofinternalcarotidarteryocclusionbysuture.PEC
7、AM一1WaSobservedwithimmunohistochemistrymethodatdifferentreperfusiontime.ResultsTherewerefcwPECAM-1positiveinthesham—operatinggroup,theexpressionofPECAM-1inthetreatmentgroupandthecontrolgroupwerelowerthanthatintheMACOgroupatdiferentreperfusiontime.(P<0.O1),andthediference
8、betweenthetreatmentgroupandthecontrolgroupwassignificant(P
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