穴位埋药对脑缺血再灌注大鼠脑梗死体积与脑微血管结构的影响

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1、2004级硕士研究生毕业论文不明显(与模型组比较，P>O．05；与腹腔注射组比较，P>O．05)，其优势作用表现在72h和120h(与腹腔注射组、电针组比较，P

2、剂一1!!竺丝翌主要塞生兰些堡奎ABSTRACTObjectireOnthebasisofcomprehensiretherapywithacupunctureforapoplexyatthepresenttime，combiningmodernpharmac0109icalresearchtopreparec01lagentetramethylpyrazineSUStained-eleasedose，toresearchtheeffectofembeddingmedicineinDazhuiandNeiguanacup

3、ointsontheinfarctv01umeanditsregulatingeffectoilmatrixmetalloproteinase-9anditsinhibitors一1afterfocalcerebralischeⅢia—reperfusion．MethodsTotally160healthySDratswereselectedanddividedrandomlyinto6groups，Thegroupsincludednormlgroup，shamgroup，model-24hgroup，model120

4、hgroup，model120hgroup，abdominalcavityinjection24hgroup，abdominalcavityinjection72hgroup，abdominalcarltyinjection120hgroup，electroacupuncture24hgroup，eleetrOacupuncture72hgroup，e】eCtroacupuncture120hgroup，embeddingmedicineinacupoints24hgroup．embeddingmedicineinacu

5、points72hgroupandembeddingmedicineinacupoints120hgroupwith10ineachgroup．ThemodelofischemiareperfusionofcerebralmiddleaftoryWaSestab／ishedbythemodifiedthreadocclusionmethod，thenembeddingmedicineinDazhuiandNeiguanacupointswithcollagentetramethylpyrazinesustained—re

6、leasedose．4ratsofeachgroupweredecollateddirectlytoextractunsaltedbraintissuewithTTCchromating；andother6ratswerereperfusedwith4％paraformaldehydeafterbeinganaesthetizedby10％chloraihydrate．andthentakenoutthebrainrapidly．Thebraintissue2mmawayfromthechiasmawascutfront

7、ally，themiddlepartleft，immersedinhardparaffin．UsedimmunohistochemistrySABCmethodtoinvestigatetheexpressionofMMP一9andTIMP—l，andtheeffectofalltheaboveindexofelectro—acupuncturewereobserved．Theentiredatumwasflnalyzedbystatistics．Results1．MCAOandreperfusioninjurycand

8、amagetherats1activitydistlnctly．Thenervesymptomsofabdominalcavityinjectiongroup，．1．2004级硕士研究生毕业论文electro—acupuncturegroupandembeddingmedicineinacupointsgroupwe