欢迎来到天天文库
浏览记录
ID:33496889
大小:337.44 KB
页数:4页
时间:2019-02-26
《妊娠相关肾损伤的临床调查》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、中国中西医结合肾病杂志2010年5月第11卷第5期CJITwN,May2010,v01.11,No.5·427·妊娠相关肾损伤的临床调查王锋①邢涛②汪年松①△黄雅娟③[摘要]目的:探讨妊娠相关性肾损伤的病因、发生率、预后转归。方法:采用回顾性分析方法调查2004年9月~2007年8月期间2988例住院妊娠患者在妊娠过程中肾损伤的发生情况。结果:75例妊娠患者存在肾损伤,占2.58%,22例为肾脏病合并妊娠。轻度肾损伤组血浆白蛋白显著高于重度肾损伤组(P值均<0.001)。各组间总胆固醇与三酰甘油差异均无统计学意义(P>0.05)。轻度肾损伤组血红
2、蛋白水平显著高于重度肾损伤组(Po.05)。与中度肾损伤组和重度肾损伤组相比,轻度肾损伤组SBP(P值分别为0.001,0.002)、DBP(P值分别为0.022,0.009)及MBP(P值分别为0.005,0.004)差异均有统计学意义,但中度肾损伤组与重度肾损伤组间差异无统计学意义。29例资料完整患者Scr均值由妊娠初期时的(176.97±108.83)pmol/L上升到妊娠后期的(193.69±148.63)tmaol/L(P<0.001);MBP均值由妊娠前
3、期的(97.00±10.91)mmHg上升到后期的(119.94±19.O0)mmHg(P<0.001)。发生子痫前期的患者共有37例(49%),其中轻度肾损伤组24例(42%),中度肾损伤组7例(58%),重度肾损伤组6例患者都存在着子痫前期。9例资料完整的患者中,肾小球滤过率(1/Scr)在妊娠晚期比早期下降的有14例(48%),其中有4例肾小球滤过率严重下降(超过25%)。结论:妊娠相关肾损伤并不少见,可随着妊娠而进展,值得关注和研究。[关键词]妊娠肾损伤肾功能AClinicalResearchonPregnancyAssociatedRe
4、nalInjuryWANGFeng,XINGTao,WANGNiansong,etalDepartmentofNephrology,SixthPeople’sHospitalAffiliatedtoShanghaiJiaotongUniversity,Shanghai(200233).Misn~crObjective:Toexplorethecauses,incidence,prognosisandoutcomeofrenalinjurypertinenttopregnancy.Meth-ods:Aretrospectiveanalysiswas
5、adoptedon2988caSesofpregnancyfromSeptember2004toAugust2007andobservetherelatedrenalinjury.Results:Seventy—fivecasesoutofthetotalhadkidneyinjury,almost2.58%,22caseswerekidneydiseasescomplicatedpregnancy.PlasmaalbuminOfthemildkidneyinjurygroupwerehigherthanthatofthesevererenali
6、njurygroup(P<0.001foral1).Thetotalcholesterol(TC)(P>0.05)andthetfiglyceride(TG)(P>0.05)amonggroupshadnostatisticalsignificance.Hemoglobininthemildkidneyinjurygroupwasfarmorethanthatinthesevererenalinjurygroup(P<0.001),butitdidnothavestatisticsignificanceeitherbetweenthemildan
7、dmoderateinjurygroups(P>0.05)orbetweenthemoderateandsevereinjurygroups(P>0.05).Comparedtomoderateandsevereinjurygroups,themildgrouphadgreatdistinctionsinthelevdsofSBP(P=0.001,0.002),DBP(P=0.022,0.009)andMBP(P=0.005,0.004).However,thereisnosuchdistinctionstatisticallybetwenthe
8、moderateandsevereinjuries.In29completely—recordedcases,thepregnancyp
此文档下载收益归作者所有