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1、120例流行性乙型脑炎流行病学和临床特征研究【摘要】目的：分析南充地区流行性乙型脑炎的流行病学及临床特征，为有效预防和治疗疾病提供理论依据。方法：收集2010-2013年在川北医学院附属医院住院治疗的120例流行性乙型脑炎患儿的临床资料，对其流行病学及临床特征进行回顾性分析。结果：120例流行性乙型脑炎患儿发病年龄主要集中在1〜8岁，所有患儿均来自农村。发病时间为7-9月，7、8、9月发病分别为26例(21.67%)、85例(70.83%)、9例(7.50%)o轻型13例，占10.83%；普通型78例，占65.00%；重型24例，占20.00
2、%；极重型5例，占4.17%。临床表现发热120例(100%),头痛101例(84.17%),呕吐109例(90.83%),抽搐105例(87.50%),意识障碍102例(85.00%),呼吸衰竭19例(15.83%),循环衰竭10例(8.33%)0血清乙型脑炎特异性IgM抗体阳性率为62.50%o85.83%的患儿住院期间发生并发症，以支气管肺炎最常见。出院时好转110例，好转率91.67%,6例患儿死亡，死亡率5.00%o结论：南充地区流行性乙型脑炎常见于8月，均来自农村地区，大多数无疫苗接种史，以普通型为主。临床表现主要有发热、头痛、呕
3、吐、抽搐及意识障碍，大多数患者预后良好。【关键词】乙型脑炎；流行病学；临床特征中图分类号R512.32文献标识码B文章编号1674-6805(2014)14-0118-02EpidemiologyandClinicalCharacteristicsof120CasesofJapaneseEncephalitis/DUANXiao-yan,ZHUQi-rong,HUANGBo,etal.//ChineseandForeignMedicalResearch,2014,12(14)：118-119[Abstract】Objective：Toanal
4、yzetheepidemiologyandclinicalcharacteristicsofJapaneseencephalitisinNanchongarea.Toprovideatheoreticalbasisforeffectivepreventionandtreatmentofcases・Method：120casesofJapaneseencephalitiswereenrolledfrom2010to2013intheAffiliatedHospitalofNorthSichuanMedicalCollege.Retrospect
5、ivemethodwasusedtoanalyzeepidemiology,clinicalcharacteristics.Result：Ofthe120casesJapaneseencephalitismainlyconcentratedintheageof1~8yearsold.Allofthepatientswerefromthecountryside.TheattackingtimewasbetweenJulyandSeptember,and26caseswereinJuly,85caseswereinAugust,9caseswer
6、einSeptember.13cases(10.83%)werelight，78cases(65.00%)weremild,24cases(20.00%)weremoderateand5cases(4.17%)weresevere.Themainclinicalmanifestationincludedfever(100%),headache(84.17%),vomiting(90.83%),convulsion(87.50%),consciousnessdisorders(85.00%),respiratoryfailure(15.83%)
7、,circulatoryfailure(8.33%).PositiverateofJapaneseencephalitisVirus-IgMinserumwas62.50%.The85.83%ofthecasesaccompaniedwithdifferentlevelscomplicationswhentheywereinhospita1.110cases(91.67%)gotbetterwhentheydischargedfromhospital,and6cases(5.00%)died.Conclusion：Mostcasesarere
8、portedfromAugustinNanchongarea.Allthecasesarefromruralandmostcaseswithunvaccinatio
