伊伐布雷定说明书（2022年-2023年）

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10ᜧvÚÛ¡¢ᑺ®N2.5mg/kg/d:¼zÜᱥᑺ®N7mg/kg/d:ÄÅḄ'᡽ᜧ20mg/kg/d:ÄÅÛ°±²᳛cÃ஺Rßឋoឋuv¡¢20,91ᡈ403/179mg/k^d,àáឋuv¡¢21,91ᡈ408/184m/kg/d,âã104ᕜåᱥ#ᐵḄæ᷈!"᳛cÃ஺pqº'iឋ!"᳛cÃḄLᓄᒹèo'᡽éஹ᜜êëஹì⊈᪝ᡂஹáïðᡂLឋñòᓄLឋஹóᜧñòᓄc´ᑺ®:ôõ§æ஺ᜧv¡¢âã104ᕜåᱥ#ᐵḄæ᷈!"᳛cÃpqº'iឋᒹèo30ng/k&/dÀ'᡽é!"᳛cÃ120/60mg/kWdÀì⊈᪝ÔÐ!"᳛cÃ1Àö÷ᳮø[N30mg/kg/dÀñòᓄùᓄ⃩ûfᶇýþ᪵
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11ë◀()*+,Ḅ⊈ë◀í⊦È11஺ïë◀᳛400ml/min,ðë◀᳛70ml/min஺ñòóôõ᣸÷ḄbᱥḄOø34%ᑺḄSᱥÃÔÕñô᣸ù஺úឋ/üúឋᑺᙠQ5mg~24mgþᑁ3¥¦ᕈឋᱯ஺ᱯḄ-ὁὅὁ65ᡈὅ75!"9AUC#Cmax:$ᙠ&'"ூὁᵨ௃஺-+,-ὅ+.,-/01◀᳛15~60mVmin:456789Ḅ:;<=>?+.456789@ᐸB⌕DEᱥS18982Ḅ1◀ᓰHὅ1◀ḄIJKLᜧN20%:ᨵᐵ"ூᵨQᵨR௃஺-S,-ὅSTUVWὅXI>YZS,-9ChildPugh[ᑖᨬ^7ᑖὅᑁ`aᔠc56789@ᐸB⌕dឋDᱥḄAUCNᓣ20fᙠgZS,-ὅgḄᦪiᨵ▲>klmnoap஺qrsZS,-ὅḄᦪi"ூᵨQᵨR௃@ூἭu௃஺/ᦔ9PK/PD:ᐵxPK/PDᐵxḄᑖ᪆z{>ᙠ56789ḄᑺRL}15mg~20mg~>᳛56789#ᐸB⌕DEᱥS18982⊈ZḄᕈឋᐵx஺ᙠKᑺR>᳛L}ᑮ>Ḽ56789⊈ᱥZḄᓣ>᳛kᡂIJL஺ᦔCYP3A4ᢓᑴᑺὶᔠᵨ>56789Ḅ☄R>᳛¡ZL஺¢gᦔCYP3A4ᢓᑴᑺὶᔠᵨ>?£¤◅ᑣᨵᡠL"ூἭu௃>ூ¨©ª⚗௃@ூᱥX¬ᵨ௃஺ூ®¯௃°±²$஺ூᒹ´௃µᛛ·¸ᒹ´>14ᱏ/ºஹ28ᱏ/ºஹ56ᱏ/ºஹ98ᱏ/ºஹ112ᱏ/º஺ூᨵᦔ¼௃36½ᨴ஺ூ᡻À᪗Â௃ÃÄŨÆ᪗ÂJX20120088஺ூÃÄŨÆÇÈ௃5mgGH20150217914ᱏ/º>28ᱏ/ºÉH20150272956ᱏ/º>98ᱏ/ºÉH201502739112ᱏ/º7.5mg:H20150218914ᱏ/º>28ᱏ/ᒾÉH20150274956ᱏ/º>98ᱏ/ºÉH201502759112ᱏ/ºூËEÌÍ௃ÎSEUWEAQÏÐÑÒᔆLesLaboratoiresServier-FranceËEÌÍ12

12ÌÍÔÕLesLaboratoiresServierIndustrieËEᙢᙬ905,RoutedeSaran,F-45520Gidy,FranceᵯÙÈṹ33155727573ÛÜÈṹ33155725765ÏᑁὶxÝÞÐÑÒ(ᜩá)ᑴᨵ▲ãäᓅæçè□êëìígî1Èíᳫðñgòó6ôõö÷ṹ100020ᵯÙG(8610)65610341ÛÜG(8610)65610348øᙬGwww.serviencom.cn13