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ID:6903159
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页数:11页
时间:2018-01-30
《meld与ctp对肝硬化患者手术预后的评估》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、MELD与CTP对肝硬化患者手术预后的评估 MELD与CTP对肝硬化患者手术预后的评估 史新河,康鹏,李朝军 (乌鲁木齐市第一人民医院外一科,新疆乌鲁木齐830000) 摘要 目的:研究终末期肝病模型及Child-Turcotte-Pugh(CTP)评分对肝硬化患者手术预后的评估。方法:对70例肝硬化病例,计算术前MELD和CTP评分,分析二者相关性及不同分组下并发症发生率差异情况。以受试者工作特征曲线(ROC)下面积衡量各模型的预测能力。结果:23例发生术后并发症。并发症、无并发症组MELD与
2、CTP分值比较差异有统计学意义。MELD<14、14≤MELD<24、MELD≥24患者并发症发生率分别为10.0%、35.7%和83.3%。CTP分级A级、B级、C级并发症发生率分别为10.3%、36.0%和68.8%。各组间差异有统计学意义。MELD与CTP评分显著相关。ROC下面积MELD为0.877,CTP为0.852,差异无统计学意义(U=0.157,P>0.05)。结论:MELD及CTP评分均能准确预测肝硬化患者围手术期并发症,临床应用宜相互结合,以进一步提高预测准确度。 关键词:肝硬化;
3、终末期肝病模型;Child-Turcotte-Pugh评分 Applicationofthemodelforend-stageliverdiseaseandChild-Turcotte-Pughsystemtoevaluatethesurgicalprognosisofpatientswithcirrhosis SHIXin-he,KANGPeng,LIChao-jun (DepartmentofSurgery,FirstHospital,XinjiangUrumqi830000) Abst
4、ract Objective:Toinvestigatetherelationshipbetweenthemodelforend-stageliverdisease(MELD)andChild-Turcotte-Pugh(CTP)scoringusedinpredicttheprognosisofpatientswithcirrhosis. Method:Collectedseventypatientswithcirrhosis.CalculationofMELDandCTPscorebefore
5、surgery,analysisofcorrelationbetweenthetwomodelsanddifferenceofthedifferentgroupsunderthesituationofincidenceofcomplications.Usetheareaunderthereceiveroperatingcharacteristiccurve(ROC)tomeasurethepredictiveabilityofeachmodel. Results:Twentythreecasesapp
6、earedpostoperativeseriouscomplications.ComplicationsandnocomplicationgroupMELDandCTPscoredifferencehasstatisticallysignificant.MELD<14,14≤MELD<24andMELD≥24groupswithcomplicationrateswere10.0%、35.7%and83.3%.CTPscoreA、BandCgroupswithcomplicationrateswere10.
7、3%、36.0%and68.8%.Thedifferencebetweeneachgroupshasstatisticallysignificant.MELDscoreshowedsignificantcorrelationswithCTP.TheareaundertheROC:MELDwas0.877,CTPwas0.852,Thedifferencebetweenthetwogroupshasnostatisticallysignificant(U=0.157,P>0.05). Conclusio
8、n:BothMELDandCTPscorescanaccuratelypredicttheshorttermprog-nosisofpatientswithlivercirrhosis. Keywords:Cirrhosis;modelforend-stageliverdisease(MELD); Child-Turcotte-Pugh(CTP)system 终末期肝病模型(MELD)作为一种新型的肝脏储备功能评
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