最新肝脂素对人和大鼠肝癌作用的研究教学讲义PPT课件.ppt

《最新肝脂素对人和大鼠肝癌作用的研究教学讲义PPT课件.ppt》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、肝脂素对人和大鼠肝癌作用的研究MaterialsandMethods(1)Table1Stagingof47Patients(43~73yr)GroupsSexStageTotalMFIIIIVHeplipin267132033Chemo.824610Control31224Total3710192847MaterialsandMethods(2)Table2.GroupingandtreatmentoftheratsGrouping(N)TreatmentWeek1-13Week13-22A(8)Maiz

2、e+DAB+HeplipinACommonFood+HeplipinAB(8)Maize+DAB+HeplipinACommonFood+HeplipinBS(8)Maize+DABCommonFoodC(7)MaizeCommonFoodTable4.Sideeffectsoftreatment(2)HeplipinChemotherapyToxicityGrade00IIIIII~IVLiverfunction33613Kidneyfunction33314SkinlesionAlopecia33521

3、Eruption33341Dryness33341Edema33431Table5HematologicalfindingsHeplipinGroup(N=33)ExaminationsBeforeAfterRBCcount(1012/L)3.8±0.24.4±0.1Hb(g/L)106.6±10.1113.3±9.9WBCcounts(109/L)4.0±0.54.9±0.6WBCclassification(%)Granulocyte(seg)60.5±0.152.0±0.1Lymphocyte32.8

4、±1.840.4±l.9Monocyte6.9±0.28.2±l.lErythrocyte22.8±l.020.0±0.5Table5Hematologicalfindings(2)ExaminationsChemotherapyGroup(N=10)BeforeAfterRBCcount(1012/L)3.7±0.23.0±0.3Hb(g/L)109.1±9.0100±10.2WBCcounts(109/L)4.1±0.42.9±0.8.WBCclassification(%)Granulocyte(se

5、g)62.1±l.68.2±2.8Lymphocyte31.3±l.814.2±2.8Monocyte5.8±0.53.0±0.8Erythrocyte22.6±l.025.0±l.0Table6BiochemicalChangesExaminationsHeplipinGroup(N=33)BeforeAfterSerumprotein(g/L)69.9±2.577.9±5.1Serumalbumin(mmol/L)42.l±5.143.1±4.5Serumglobulin(mmol/L)3.2±0.13

6、.8±0.1Bilirubin(mg/dl)1.2±0.l0.9±0.2Thymolreaction(U)10±l.44.4±l.3Alt(U)83.3±15.373.9±1.5Ast(U)69.5±14.244.3±6.7Bloodurea(mol/L)5.0±1.24.5±1.1Creatinine(umol/L)80±3050±20Table6BiochemicalChangesExaminationsHeplipinGroup(N=33)BeforeAfterSerumprotein(g/L)70.

7、0±2.362±1.8Scrumalbumin(mmol/L)43.0±4.240±2.5Serumglobulin(mmol/L)3.2±0.32.2±0.4Bilirubin(mg/dl)l.3±0.2l.4±0.2Thymolreaction(U)10±l.213±l.8Alt(U)80±16.1120±13Ast(U)68±1688±6.2Bloodurea(mol/L)4.8±1.47.4±1.5Creatinine(umol/L)78±2096±20Table6BiochemicalChange

8、sTable7ChangesoftumorsizeinHeplipinGroupTumorSizeBeforeAfterSuppression(%)Longitudinald(cm)6.2±0.85.0±0.6*60%Crossd(cm)5.8±0.74.6±0.5*60%Square(cm2)38.7±8.525±5.660%*p<0.05Table8Clinicalassessmentsontumorsup