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时间:2017-12-20
《降钙素原在脓毒血症患儿早期预后预测中应用价值》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、降钙素原在脓毒血症患儿早期预后预测中应用价值 广东省肇庆市第二人民医院,广东肇庆526040[摘要]目的探讨降钙素原(PCT)在脓毒血症患儿早期预后预测的应用价值,以期为脓毒血症患儿疾病的诊断治疗提供依据。方法2012年10月~2013年10月肇庆市第二人民医院收治的脓毒血症患儿以及同期40例非脓毒血症患儿(非脓毒血症组)为研究对象,其中60例脓毒血症患儿为脓毒血症组,根据患病性质分为细菌性脓毒血症组(40例)、非细菌性脓毒血症组(20例);60例脓毒血症患儿中治疗痊愈的为存活组,死亡的为死亡组。根据新生患儿危重病例(NCIS)评分法对60例脓毒血症患儿患病程度进行评定;检测细菌性脓
2、毒血症组、非细菌性脓毒血症组以及非脓毒血症组患儿的血清PCT、白细胞(WBC)、C反应蛋白(CRP)水平,并对数据进行统计分析。结果60例脓毒血症患儿入院治疗痊愈的41例(存活组),死亡19例(死亡组);细菌性脓毒血症组、非细菌性浓度血症组血清PCT水平[(11.86±5.92)、(2.14±1.33)ng/mL]和非脓毒血症组的血清PCT水平[(0.37±0.22)ng/mL]相比,差异有统计学意义(P0.05)。1例患儿NCIS评分为非极危重,其血清PCT水平则超过14.8611ng/mL患儿最后死亡;NCIS评分为极危重患儿6例,其血清PCT水平未超过14.86ng/mL,治疗后
3、患儿存活。结论血清PCT在脓毒血症患儿早期预后预测具有显著的应用价值。[关键词]降钙素原;脓毒血症;预后;预测;应用[中图分类号]R978.1[文献标识码]A[文章编号]1673-7210(2014)03(b)-0044-04ApplicationvalueofprocalcitoninonearlypredictionofinsepsispatientsYUYanhongCHENYingLIANGYanfenTheSecondPeople’sHospitalofZhaoqingCity,GuangdongProvince,Zhaoqing526040,China[Abstract]O
4、bjectiveToinvestigatetheapplicationvalueofprocalcitoninonearlypredictionofinsepsispatients,inordertoprovidethebasisforthediagnosisandtreatmentofdiseaseinchildrenwithsepsis.MethodsFromOctober2012toOctober2013,intheSecondPeople’sHospitalofZhaoqingCity,60casesofchildrenwithsepsis(sepsisgroup)and40c
5、asesofnon-sepsis(non-sepsisgroup)inthesameperiodwereselected,andthe60casesofchildrenwithsepsisweredividedintobacterialsepsisgroup(40cases),non11bacterialsepsisgroup(20cases);60casesofchildrencuredwereassurvivalgroup,andchildrendiedwereasdeathgroup.Accordingtothenewbornchildrenwithcriticalcases(N
6、CIS)evaluationmethodwastoassesshowsickchildrenwere.TheserumPCT,theWBCandCRPlevelsofthreegroups(bacterialsepsisgroup,nonbacterialsepsisgroupandnonsepsisgroup)weredetected,andthesedatewerestatisticalanalyzed.Results60casesofchildrenwithsepsiscuredwere41(survivalgroup),diedwere19(deathgroup);theser
7、umPCTlevelsofbacterialsepsisgroupandnonbacterialsepsisgroup[(11.86±5.92),(2.14±1.33)ng/mL]werecomparedwiththatofnonsepsisgroup[(0.37±0.22)ng/mL],thedifferenceswerestatisticallysignificant(P0.05).1casewithnonseveresepsisNCISs
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