加味温胆汤联合尼莫地平片治疗非痴呆型血管性认知功能障碍的临床效果观察.pdf

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1、中国当代医药2014年l0月第21卷第28期·中医中药·加味温胆汤联合尼莫地平片治疗非痴呆型血管性认知功能障碍的临床效果观察赵丽群饶凯华刘海顺江西中医药大学附属医院神经内科，南昌330006[摘要】目的观察加味温胆汤联合尼莫地平片治疗非痴呆型血管性认知功能障碍(VCIND)痰瘀阻络型患者的临床效果。方法将89例VCIND痰瘀阻络型患者随机分为中医治疗组29例、西医治疗组30例和中西医治疗组30例。中医治疗组以温胆汤加味，西医治疗组口服尼莫地平片，中西医治疗组以加味温胆汤和西药尼莫地平为主，3组均以1O周为1个疗程。治疗前后采用

2、日常生活活动能力(ADL)评定量表、蒙特利尔认知评估量表(MoCA)进行评分。结果3组治疗后ADL及MoCA评分均高于治疗前，差异有统计学意义f

3、servationofJiaweiWendantangcombinedwithnimodip-ineintreatmentofvascularcognitiveimpairmentnodementiaZHA0Li——qunRA0Kai——huaLIUHai——shunDepartmentofNeurology，AffiliatedHospitalofJiangxiUniversityofTraditionalChineseMedicine，Nanchang330006，．China【Abstract】ObjectiveToob

4、servetheclinicaleffectofJiaweiWendantangcombinedwithnimodipineinthetreatmentofvascularcognitiveimpairmentnodementia(VCIND)．Methods89casesofpatientswithbloodstasisandphlegmstagnancyofVCINDwereselectedandrandomlydividedintogroupofTCM(29cases)，westelTlmedicinegroup(30c

5、as—es)，andTCMcombinedwithwesternmedicinegroup(30cases)．GroupofTCMwastreatedbyJiaweiWendantang，west-ernmedicinegroupwastreatedbynimodipine，andTCMcombinedwithwesternmedicinegroupwastreatedbyJiaweiWendantangcombinedwithnimodipine．Threegroupswerereceivedtreatmentfortenw

6、eeksofonecourse．Activitiesofdailyliving(ADL)andMontrealcognitiveassessment(MoCA)wereevaluatedbeforeandaftertreatment．ResultsADLandMoCAscoreofthreegroupsaftertreatmentwereincreasedcomparedwithbeforetreatment(P<0．05)；andthescoreofTCMcombinedwithwesternmedicinegroupwas

7、betterthanthatofgroupofTCMandwesternmedicinegroup(P<0．05)．Duringtreatment，thethreegroupshadnosignificantadversereactions．ConclusionJiaweiWendantangcombinedwithnimodipineinthetreatmentofVCINDissafeandeffective．【Keywords】Vascularcognitiveimpairmentnodementia；Bloodstas

8、isandphlegmstagnancy；Nimodipine；Wendantang非痴呆型血管性认知功能障碍(vascularcognitive前应用最广泛的西药尼莫地平被认为是治疗VCINDimpairmentnOdementia．VCIND)指由脑血管源性损伤效果较好的