加味温胆汤治疗抑郁症30例临床观察

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1、加味温胆汤治疗抑郁症30例临床观察)摘要：［日的］观察加味温胆汤治疗抑郁症的临床疗效。［方法］将60例抑郁症患者随机分为屮药组和対照组，対照组30例给予盐酸氟西汀胶囊，屮药组30例给予加味温胆汤，两组疗程均为6周。治疗前及治疗后2,4,6周末采用汉密尔顿抑郁量表(HAMD)于进行评分；治疗前后采用屮医症候量表、神经心理学测验、抗郁药副反应评定最表(SERS)评价疗效和不良情况。［结果］治疗6周后，屮药组与対照组临床疗效和当，可明显改善治疗前HAMD评分，两组未显示统计学差异；中药组在治疗4周后对中医症候具有明显改善作用，与对照组有明显差异(P<0.05)；两组的基本执行功能总分值存

2、在差异(P<0.05),主耍表现在WCST总正确数、TOH平均计划时间、TMT-B错误数方面屮约纽得分高于对照纽；中药组的(SERS址表评分)不良反应发生率(13.4%)明显低于对照组(30.4%)。［结论］加味温胆汤对抑郁症具有良好的临床治疗效果。关键词：抑郁症；加味温胆汤；緘西汀；临床观察中图分类号：R277.7ClinicalObservationofTreating30CasesofDepressionwithJiaweiWendanDecoctionTangJiuhuii,ZhangLipingi,WuPeiram,YanHong2(1.TianjinUniversity

3、ofTraditionalChineseMedicine,Humanisticmanagementcollege,Tianjin300073;2.FirstTeachingHospitalofTianjinUniversityofTraditionalChineseMedicine,TianJin300073)Abstract:Objective:ToinvestigatecurativeeffectoftreatingdepressionwithJiaweiWendanDecoction.Methods:60depressionpatientswererandomlydivide

4、dintotraditionalChinesemedicinegroupandcontrolgroup・Controlgroupof30patientsweretreatedwithFluoxetine;IraditionalChinesemedicinegroupof30patientsweretreatedwithJiaweiWendanDecoction.Bothgroupsweretreating6weeksasacourseoftreatment.Toevaluatecurativeeffectandsideeffect,Hamilton(HAMD)scalescorew

5、eremeasuredinbothgroupsbeforetreatmentandafterattheendofthe2nd,4th,6thweek,TCMsyndromes,neuropsychologicaltests,SERSweremeasuredinbothgroupsaftertreatment.Results:Attheendofthe6thweek,wefoundthattherewerenosignificantdifferencesbetweenthetwogroups(P>0.()5)inthecurativeeffectandthescoresofHAMD;

6、andfromthe4thweek,thechangesdifferencesofTCMsymptomsbetweentwogroupsweresignificant(P<0.05);andinthetraditionalChinesemedicinegroupthescoresofbasicneurocognitivefunctioning,suchasthecontinueerrorsofWCST,totalscoresofTOH,errorsofTMT-B,wereobviouslyhigherthanthecontrolgroup(P<0.05).Howcvcr,theex

7、tentofadversereaction(SERS)inthetraditionalChinesemedicinegroup(13.4%)waslowerthanthatinthecontrolgroup(30.4%).Conclusion:JiaweiWendanDecoctionhasagoodcurativeeffectintreatingdepression.Keywords:Depression;JiaweiWendanDecoction;Fluoxeti