腹腔镜与开腹结直肠癌根治术的近远期疗效比较.pdf

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1、趟垡地鳖盘查(皇王题立!Q!；生!旦筮堡鲞箜!塑』望螬Qnc!!(垦!!!!翌也!!!型!!)：丛塑尘至Q!!，y!!垒：№．!2l▲论著-腹腔镜与开腹结直肠癌根治术的近远期疗效比较王仁辉温宜清邓浩财【摘要】目的探讨分析腹腔镜下结直肠癌根治的安全性和可行性，对比其与开腹手术的近远期疗效。方法回顾性分析我院2006年1月至2011年12月间结肠及中上段直肠癌根治术患者的临床资料，其中开腹手术120例，腹腔镜下手术76例。分析比较两组患者的I临床病理资料、围手术期情况及近远期生存情况。结果两组患者年龄、性别

2、比较无统计学差异。腹腔镜组平均手术时间大于开腹组，分别为(226．28±61．09)rain和(193．50±53．79)min；术中失血量腹腔镜组小于开腹组，分别为(84．00±28．41)ml和(187．60±37．27)ml；术后住院时间腹腔镜组小于开腹组，分别为(7．55±2．04)d和(8．40±3．39)d。两组患者肠管近端及远端切缘长度、清扫淋巴结数目以及术后感染性和非感染性并发症发生率比较，差异无统计学意义。开腹组与腹腔镜组结直肠癌患者术后3、5年生存率分别为76．8％、65．7％和76

3、．6％、71．2％(P>O．05)；Duke’SA、B、C各期两组患者生存率比较无统计学差异。结论腹腔镜结直肠癌根治手术安全可行，具有出血少、术后恢复快等优点，肿瘤安全性、并发症发生率及术后近远期疗效不亚于开腹手术。【关键词】结肠癌；中上段直肠癌；腹腔镜；开腹手术；并发症；预后ComparisonofclinicalefficacyoflaparoscopicandopenradicalresectionforcolorectalcancerWANGRen—hui，WENyi—qing，DENGHao—

4、cai．DepartmentofGeneralSurgery，thePeople’sHospitalofHengLi，Dongguan523460，China．Correspondingauthor：WANGRen—hui，Email：479548254@qq．com【Abstract】ObjectiveToinvestigatethesafetyandfeasibilityoflaparoscopicradicalresectionforcolonicandupper／medianrectalcanc

5、er，andcomparetheshortandlong—termclinicalefficacyoflaparoscopicandopenoperations．MethodsClinie叩athologicaldataof196colorectalcancerpatientsundergoinglaparoscopic(n=120)andopen(n=76)radicalresectioninourhospitalfromJanuary2006toDecember2011wereanalyzedret

6、rospectively．Theperioperativeclinicopathologicalcharacteristics，andsurvivaltimewerebetweenthetwogroups．ResultsTherewerepostoperativecomplicationscomparednosignificantdifferencesinageandgenderbetweenthetwogroups．Theoperatingtimeintheinthelaparoseopicgroup

7、was(226．28±61．09)min，significantlylongerthan(193．50±53．79)minopengroup．Thebloodlosswas(84．00±28．41)mlinthelaparoscopicgroup，significantlylessthan(187．60±37．27)mlintheopengroup．Thepostoperativehospitalstaywas(7．55±2．04)dinthelaparoscopicgroup，shorterthanf

8、8．40±3．39)dinthewerenodifferencesinsignificantlyopengroup．Theresignificantproximalanddistalincisionmargin，numberofdissectedlymphnodes，andpostoperativecomplicationsbetweenthetwogroups．The3一and5-yearsurvivalrateswere76．6％and