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1、中国组织工程研究笫,8誊第73期2014—03—26出版ChineseJournalofTissueEngmeefingResearchMarch26,2014Vo1.18,No.13www.CRTER.orgAdministrationofaspirinandrivaroxabanpreventsdeepveinthrombosisaertotalkneearthroplastyzouYue,TianShao·qi,WangYuan-he,LiuJiang-jun,SunKangDepartmentofJointSurgery,theAfiliatedHospitalofQmgdaoU
2、niversity,Qingdao266003,ShandongProvince,ChinaAbstractBACKGROUND:Todate,rivaroxabanhasbeenaclinicallycommonanticoagulantinChina;however,efectiveZouYue.Studyingforprophylaxisforvenousthrombosisisassociatedwithamarkedlyhigherincidenceofperioperativehemorrhagicmaster’sdegree,DepartmentofJointSurgery
3、,theAffiliatedcomplications.Althoughithasbeenreportedthataspirinefectivelypreventsdeepveinthrombosisandpulmona~embolism,theuseofaspirinasaroutinedrugforvenousthrombosisaftertotalkneearthroplastyisHospitalofQingdaoUniversity,Qingdao266003.stillcontroversia1.ShandongProvince,ChinaOBJECTIVE:Tocompar
4、etheeficacyandsafetvofaspirinandrivaroxabanforpreventionofdeepveinthrombosisaftertotaIkneearthroplasty.Correspondingauthor:SunMETHODS:Totally324patientswithosteoarthritiswhounderwentprimaryunilateraItotalkneearthroplastyKang,MD.。Chiefphysician,wererandomlydividedintothreegroups.Twelvehoursafterth
5、esurgery,threegroupsweregivenaspirin,Doctoralsupervisor,rivaroxabanandlow-molecular-weightheparinrespectively.Allthreegroupsweretreatedfor14days.andallofDepartmentofJointSurgery,thepatientswerefoIlowedfor4weeks.theAft]liatedHospitalofRESULTSANDCONCLUS10N:ComparedwiththeIow-mOlecuIar-weIghtheparin
6、group,theIncidenceofdeepQingdaoUniversity,Qingdaoveinthrombosiswaslower(P<0.05),buthiddenbloodlOSSandwoundcomplicationsweremorecommon(P<266003,ShandongProvinceChina0.051intherivaroxabangroup.TherewerenosignificantdifferencesbetweentheIow-molecular—weighIheparingroupandaspiringroupintheincidenceof
7、deepveinthrombosis,hiddenbloodlOSS,woundcomplicationsordoi:103969/].issn.2095-4344incidencasoflowerIimbswellingandsubcutaneousecchymosis(P>0.O5).Theresultsconfirmedthat201413008rivaroxabanhasapositiveantic0aauIati0nefe
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