甲胎蛋白阴性和阳性原发性肝细胞癌的超声特征比较.pdf

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1、圭垦堕堂堡塑一~：2014年第3o卷第6期Chin1MedImagingTechnol，2014，Vol30，No6·877·◆：◆腹部影像学Ultrasonicfeaturesofprimaryhepat0ceJJuJarcarcinomawithnegativeandpositiveexpressionofalphafetoprotein：ComparisonanalysisWANGXiao—mat'l，ZHENGZhe—lan，GAOFeng。，YUANHua—qin(1．DepartmentofUltrasound，theFirstAffil

2、iatedHospital，ZhejiangUniversity，Hangzhou310003，China；2．DepartmentofUltrasound，theAffiliatedHospitalofHangzhouNormalUniversity，Hangzhou310015，China)]-Abstract]ObjectiveTocompareultrasoundfeaturesofprimaryhepatocellularcarcinoma(HCC)withpositiveornega—liveexpressionofd—fetoprote

3、in(AFP)．MethodsTotally103patientswithHCCconfirmedbypathologywerecollected．including43negative-AFPHCCand60ofpositive-AFPHCC．UltrasoundandCEUSfeaturesofthetwokindsofHCCwereanalyzedandcompared．ResultsRegularultrasoundshowedmostofnegative-AFPHCCweresinglelesion(38／43，88．37)withdiam

4、eter≤3cm(32／43，74．42)andregularshape(31／43，72．09)，mainlyshowedhomogeneousecho(33／43，76．74Ao)．Inmostofnegative—AFPHCC，nonecrosisandhemorrhagewereobserved(34／43，79．07％)，richcenterbloodflowinthetumorcouldbeseen(31／43，72．09)，67．44(29／43)withoutinvasionnormetastasis．Mcan—while，mosto

5、fpositive-AFPHCCwerealsosinglelesion(37／60，61．67％)withdiameter>3cm(37／60，61．67)andirregularshape(41／60，68．33)，andthetumorsmainlyshowedheterogeneousecho(39／60，65．O0％)．Amongpositive—AFPHCC，necrosisandhemorrhagewerecommon(49／60，81．67)，andmostshowedsurroundrichbloodflow(39／60。65．OO

6、)．Invasionormetastasisoccurredinmostofpositive-AFPHCC(33／60，55．00)．Therewerestatisticaldiffer—encesoftheaboveultrasoundfeaturesbetweennegative—andpositive-AFPHCC(allP<0．05)．InCEUS，mostofnega—tive-AFPHCC(19／29，65．52)showed”fastwash—inandslowwash—out”，whilemostofpositive—AFPHCC(3

7、3／44，75．OO)showed”fastwash—inandfastwash—out”(P<0．05)．ConclusionThereweredifferencesofsomeultrasonicfea—turesbetweennegative-andpositive-AFPHCC．AFPexpressioncanbeassessedinitiallythroughultrasound．[Keywords]Carcinoma，hepatocellular；Alpha～fetoproteins；Ultrason0graphy甲胎蛋白阴性和阳性原发性

8、肝细胞癌的超声特征比较王晓墁，郑哲岚，高枫。，袁华琴。(1．浙江大学医学院附属第一医院超声科，浙江杭州310