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页数:10页
时间:2020-05-24
《光动力疗法联合支架置入治疗食管癌所致气道狭窄的效果观察.doc》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、光动力疗法联合支架置入治疗食管癌所致气道狭窄的效果观察[摘要]目的比较单纯支架置入与光动力治疗联合支架置入治疗食管癌所致气道狭窄的效果。方法2009年10月〜2014年10月,收集武安市第一人民医院胸外科食管癌引起中央气道狭窄患者25例,将其随机分为两组,12例(试验组)给予支架置入后行光动力治疗,13例(对照组)行单纯支架置入,比较两组患者的气促评分情况、平均稳定期、平均生存期及并发症发生率。结果两组的气促评分改善情况差异无统计学意义(P>0.05);试验组患者的平均稳定期、平均生存期明显延长(PC0.05),支气管再狭窄发生率降低(P3.05)。结论光动力治疗联合支架置入是治疗食管癌
2、所致气道狭窄的一项有效姑息治疗方法,可延长平均稳定期和平均生存期,降低支气管再狭窄发生率。[关键词]光动力治疗;支架置入;食管肿瘤;气道阻塞[中图分类号]R735.1[文献标识码]A[文章编号]1674-4721(2015)05(b)-0057-04EffectobservationofphotodynamictherapycombinedwithstentimplantationinthetreatmentofairwaystenosiscausedbyesophagealcancerKONGGuo-pingSUNJianADepartmentofThoracicSurgery,the
3、FirstPeople'sHospitalofWuanCityinHebeiProvince,Wuan056300,China[Abstract]ObjectiveTocomparetheeffectofsimplestentimplantationandphotodynamictherapy(PDT)combinedwithstentimplantationinthetreatmentofairwaystenosiscausedbyesophagealcancer.MethodsFromOctober2009toOctober2014,25patientswithcentralairw
4、aystenosiscausedbyesophagealcancertreatedindepartmentofthoracicsurgeryoftheFirstPeople'sHospitalofWuanCitywereselectedandtheywererandomlydividedintotwogroups.12patients(experimentalgroup)weregivenPDTafterstentimplantation,whiletheother13patients(controlgroup)wasgivensimplestentimplantation.Shortb
5、reathscore,meanstabletime,meansurvivaltimeandincidencerateofcomplicationbetweentwogroupswascomparedrespectively.ResultsTherewasnostatisticaldifferenceofshortbreathscorebetweentwogroups(P>0.05).Meanstabletimeandmeansurvivaltimewassignificantlyprolonedinpatientsofexperimentalgroupandincidencerateof
6、bronchialstenosisagainwasobviouslydecreased(P<0.05).ConclusionPhotodynamictherapycombinedwithstentimplantationisaneffectivepalliativetreatmentmethodoftreatingairwaystenosiscausedbyesophagealcanceranditcanprolongthestabletimeandmeansurvivaltime,andreducetheincidencerateofbronchialstenosisagain.[Ke
7、ywords]Photodynamictherapy;Stentimplantation;Esophagealneoplasm;Airwayobstruction食管癌常侵犯气管和主支气管,导致气道狭窄,临床常出现呼吸困难,可降低患者生活质量并缩短其生存期。气管支架能扩张狭窄的管腔,缓解患者的呼吸困难症状,然而肿瘤组织生长可使支架被压扁,并可进入支架网眼而导致气道再狭窄。由于大多数患者已经过手术、放疗及化疗等多种方式综合治疗,患者体
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