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时间:2020-05-15
《甲亢患者心率变异性及QT间期离散度分析.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·26·生国堡应Q年第9卷第l3期ChinJModDrugAppl,Jul2015,V01.9,N0.13甲亢患者心率变异性及QT间期离散度分析杜琼颖井艳【摘要】目的研究甲状腺功能亢进(甲亢)患者心率变异性及crr间期离散度(QTd)的变化。方法52例甲亢患者为甲亢组,49例健康体检者为对照组,对其24h动态心电图以及常规标准l2导联心电图进行回顾性分析,分析比较两组患者的最小心率、最大心率、平均心率值;心率变异性时域指标全部窦性心搏RR间期(简称NN间期)的标准差(SDNN)、RR间期平均值标准差(SDANN)、相邻NN之
2、差>50ms的个数占总窦性心搏个数的百分比(PNN50)、相邻RR间期差值的均方根fRMSSD)以及最大QT间期(QTmax)、最小QT间期(QTmin)、QT间期离散度(QTmax—QTmin)。结果甲亢组患者的最小心率、最大心率、平均心率均较对照组增高,差异具有统计学意义(P<0.05);SDNN、PNN50、SDANN、RMSSD均较对照组降低,差异具有统计学意义(尸<0.05);QTd较对照组增大,差异具有统计学意义(P<0.05)。结论甲亢患者心率变异性及QT离散度异常率较高,自主神经对心脏的调节能力降低,易发生恶
3、性心律失常及心源性猝死,临床上应对该类患者给予高度重视,减少猝死的发生。【关键词】甲状腺功能亢进;心率变异性;QT间期离散度;自主神经DOI:10.14164/j.cnki.cnl1—5581/r.2015.13.Ol3AnalysisofheartratevariabilityandQTintervaldispersioninhyperthyroidismpatientsDUQiong-ying,JlNGYah.DepartmentofElectrocardiogram,TheSecondAffiliatedHospita
4、lofZhengzhouUniversity,Zhengzhou450014,China【Abstract】ObjectiveToresearchthechangesofheartratevariabilityandQTintervaldispersion(QTd)inhyperthyr0idismpatients.MethodsTherewere52hyperthyroidismpatientsashypenhyroidismgroupand49healthypeopleascontrolgroup.Aretrospect
5、iveanalysiswasmadeontheir24hdynamicelectrocardiogramandconventionalstandard12-leadelectrocardiogram.Minimumheartrate,maximumheartrate,andaverageheartratevalues,standarddeviationinallsinuscardiacRRinterphase(NNinterva1)(SDNN)inheartratevariability,standarddeviationa
6、verageinRRinterphase(SDANN),proportionofadjacentNNdifference>50msintotalnumberofsinusheartbeat(PNN5o),adjacentRRinterphaseroot—mean—square(RMSSD),maximumQTinterval(QTmax),minimumQTinterval(QTmin),QTintervaldispersion(QTmax-QTmin)wereanalyzedandcomparedinthetwogroup
7、s.ResultsThehyperthyroidismgrouphadhigherminimumheartrate,maximumheartrate,andaverageheartratethanthecontrolgroup,andtheirdifferencehadstatisticalsignificance(P<0.05).ItsSDNN,PNN50,SDANN,andRMSSDwerealllowerthanthecontrolgroup,andtheirdifferencehadstatisticalsignif
8、icancefP<0.05).ItsQTdwashigherthanthecontrolgroup,andtheirdifferencehadstatisticalsignificance(P
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