欢迎来到天天文库
浏览记录
ID:55098881
大小:645.34 KB
页数:5页
时间:2020-05-09
《超声内镜引导下经支气管针吸活检术对肺小细胞癌的诊断价值及病理特征.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、JournalofChina-JapanFriendshipHospital,2015Jun,Vo1.29,No.3中日友好医院学报2015年第29卷第3期147超声内镜引导下经支气管针吸活检术对肺小细胞癌的诊断价值及病理特征牛云,史艳芬,张红雷,冯宏响。(1.中日友好医院病理科;2.胸外科,北京100029)摘要目的:探讨超声内镜引导下经支气管针吸活检术(EBUS—TBNA)细胞学检查和组织学检查诊断肺小细胞癌的价值。方法:回顾性分析2013年1月~2014年11月间确诊的肺小细胞癌患者的EBUS—TB
2、NA检查结果,分析EBUS—TBNA细胞学和组织学检查的病理特征,比较两种检查的诊断符合率。结果:28例患者行E—BUS—TBNA细胞学检查,诊断符合率78.6%;25例行组织学检查,诊断符合率96.0%。应用EBUS—TBNA细胞学及组织学检查的25例患者,符合率100.0%。病理特征:细胞小,胞质稀少,核圆形、卵圆形或梭形,染色质深染,细颗粒状,通常不见核仁,核分裂像常见,易挤压、拉丝,细胞间互相镶嵌。免疫组化结果:CK阳性率100%,CD56阳性率90%,Syn阳性率55%,,ITI’Fl阳性率89
3、.47%,CgA阳性率60%。结论:对于肺门,纵隔淋巴结肿大的肺小细胞癌患者,联合应用EBUS—TBNA细胞学及组织学检查,可提高诊断率,微创高效。关键词:超声内镜引导下经支气管针吸活检术;肺小细胞癌:组织学;细胞学中图分类号:R604文献标识码:A文章编号:1001—0025(2015)03—0147—04doi:10.3969/j.issn.1001—0025.2015.03.006Thevalueofendobronchialultrasound-guidedtransbronchialneedle
4、aspirationinthediagnosisofsmallcelllungcancerandthepathologicalcharacteristics//NIUYun,SHIYan-fen,ZHANGHong-lei,etal//JournaiofChina-JapanFriendshipHospital,2015Jun,29(3):147-150Abstract0bjective:Toexplorethevalueofendobronchialultrasound-guidedtransbronc
5、hialneedleaspiration(EBUS—TBNA)indiagnosisofsmallcelllungcancer.Methods:FromJanuary2013toNovember2014,thepa-tientswhounderwentEBUS-TBNA,finallydiagnosedassmallcelllungcancerinthehospital,wereretrospec-tivelyenrolledinourstudy.Toanalyzethepathologicalchara
6、cteristicsbyusingEBUS-TBNAcytologyandhis—tologyandcomparethediagnosisratebetweenthetwomethods.Results:Twenty-twocaseswerediagnosedassmallcelllungcancerin28patientswhounderwentEBUS-TBNAcytology.Thediagnosticratewas78.6%.Twenty—fivecasesin28patientsunderwen
7、tEBUS-TBNAhistology,and24cases(96.0%)weredisgnosed.Whileallthe25caseswerediagnosedassmallcelllungcanerbyusingEBUS-TBNAcytologyandhistology.Thediagnosticratewas100.0%.Thepathologicalcharacteristics:tumourcellsweresmall,round,ovoidandhadscantcytoplasm,round
8、,ovoidorspindlednuclei.Nuclearchromatinwasfinelygranularandnucleoliwereabsentorinconspicuous.Cellborderswererarelyseenandmitoseswere~equent.CeHswerealwaysinlaidingwitheachother.Immunohistochemicalfeatures:thepositiv
此文档下载收益归作者所有