健脾化瘀中药治疗肝癌临床研究-论文.pdf

《健脾化瘀中药治疗肝癌临床研究-论文.pdf》由会员上传分享，免费在线阅读，更多相关内容在应用文档-天天文库。

1、新中医2013年12月第45卷第12期JOURNALOFNEWCHINESEMEDICINEDecember2013Vo1．45No．12·129·健脾化瘀中药治疗肝癌临床研究钟崇’，李惠东’，陈智远2，郭荣平21．广州中医药大学第一附属医院肝胆外科，广东广州5104052．中山大学肿瘤防治中心肝胆外科，广东广州510061[摘要]目的：观察手术并健脾化瘀中药治疗肝癌的临床疗：故。方法：将120例患者随机分为2组各6O例，治疗组采用手术并健脾化瘀法中药治疗，对照组采用手术治疗，观察治疗周期为1年，以无瘤生存率和生存率作为主要评价指标分析疗效。结果：至随访结束，复发率治组为8

2、0．0％，对照组为93．3％，2组比较，差异有显著性意义(P

3、[文献标识码]A[文章编号_】0256—7415(2013)12一O129—04ClinicalStudyofChineseHerbswithActionsofInvigoratingSpleenandRemovingBloodStasisinTreatingHepat0ce¨uIarCarcinomaZHONGChong，LIHuidong，CHENZhiyuan，etalAbstract：Objective：ToinvestigatetheclinicaleffectofqepatectomycombinedwithChineseherbswiththeactionso

4、finvigoratingspleenandremovingbloodstasisforthetreatmentofhepatocellularcarci-nomafHCC)．Methods：OnehundredandtwentyHCCpatientswererandomizedintotreatmentgroup(n=60)andcontrolgroup(n=60)．Bothgroupreceivedhepatectomy．ThetreatmentgroupreceivedChinesemedicinaltherapy0finvigoratingspleenandremo

5、vingbloodstasisasadjuvanttreatmentaftersurgery．Theobservationtimelastedoneyear．Tumor—freesurvivalrate(TFoR)andoverallsurvivalrate(OSR)wereob—servedtoevaluatethetherapeuticeffect．Results：Attheend3ffollow—up，therecurrenceratewas80％inthetreatmentgroupandwas93．3％inthecontrolgroup，thedifference

6、beingsignificant(P<0．O5)．Inthetreatmentgroup，TFSRfor1，3and5year(s)was4．8％，29．6％，14．1％respectively，andtheme—diantumor—freetimewas22months；inthecontrolgroup，theTFSRfor1，3and5year(s)was71．7％，23．3％，4．8％，respectively，andmediantumor-freetimewas15months，thedifferencebeingsignifi—cantinthetwogroup

7、s(P<0．05)．Theone-．3一and5一yearsurvivalratesandmediansurvivaItimewere96．7％，64．4％，40．1％and49monthsinthetreatmentgroup，andwere93．3％，62．9％，31．9％and44monthsinthecontrolgrouprespectively，thedifferencebeingsignificant(P<0．05)．Conclusion：Thehep—atectomycombinedwithChin