脑肿瘤立体定向靶向微创手术临床应用分析-论文.pdf

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1、临床医学Chine&ForeignMedicalTreatment口—■■固■譬誓_脑肿瘤立体定向靶向微创手术临床应用分析成友军郭旭东王金伟广州市脑科医院神经外科．广东广州510370f摘要】目的探讨立体定向靶向微创手术应用于脑肿瘤治疗的临床效果。方法选择于2008年3月～2O13年1月在该院接受治疗的脑肿瘤患者66例，随机分成对照组和观察组各33例，对照组通过开颅手术治疗，观察组则通过脑肿瘤立体定向靶向微创手术治疗，对比两组患者的存活率和术后复发率，同时观察两组患者治疗前后生活自理能力和神经功能的改善情况。结果观察组患者的存活率为87．9％，显著高于对照组的69．7％，观察组

2、患者术后的复发率为15．2％，显著低于对照组的36．4％，比较差异有统计学意义(P<0．05)；两组患者的ADL评分提高、CCS评分降低，但是观察组的变化幅度更大，比较差异有统计学意义(P<0．05)。结论立体定向靶向微创手术在脑肿瘤的治疗中具有较高的应用价值，能够显著降低死亡率和复发率，促进术后患者的康复预后。f关键词】脑肿瘤；立体定向；微创手术；临床分析[中图分类号】R739[文献标识码1A[文章编号11674—0742(2O14)O7(b)一0073—03TheAnalysisoftheClinicalApplicationofStereotacticTargetingM

3、inimallyInvasiveSurgeryforBrainTumorsCHENGYoujunGUOXudongWANG]inweiDepartmentofNeurosurgery，GuangzhouBrmnHospital，Guangzhou，GuangdongProvince，510370，China。[Abstract]ObjectiveToobservetheclinicalefectofstereotactictargetingminimallyinvasivesurgeryforthetreatmentofbraintumors．Methods66patients

4、withbraintumoradmittedinourhospitalfromMarch，2008toJanuary，2013wereselectedandran—domlydividedintothecontrolgroupandtheobservationgroupwith33casesineach．Thecontrolgroupweretreatedbycranioto—my，andtheobservationgroupweretreatedbystereotactictargetingminimallyinvasivesurgery．Thesurvivalrateand

5、recurrencerateoftwogroupsofpatientswerecompared，andtheself-careabilityandimprovementofneurologicalfunctionbeforeandaftertreatmentofbothgroupsofpatientswereobserved．ResultsThesurvivalrateoftheobservationgroup'spatientswas87．9％．sign[f-icanflyhigherthanthecontrolgroup's69．7％，therecurrencerateof

6、patientsintheobservationgroupwas15．2％，significantlylow-erthanthecontrolgroup's36．4％，thedifferencesweresignificant(P

7、argetingminimallyinvasivesurgeryhasahighvalueinthetreatmentofbraintumors，whichcansignificantlyre—ducethemortalityandrecurencerate，andpromotethepostoperativerehabilitationandprognosisofthepatients．[Keywords]Braintumor；Stereotactic；Minimallyinvasives