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时间:2020-04-21
《不同剂量右美托咪定复合罗哌卡因对小儿骶管阻滞效应的比较-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、《中国医学创新》第11卷第16期(总第298~J)2014~1E6fl临床研究Linchuangyanjiu不同剂量右美托咪定复合罗哌卡因对小儿骶管阻滞效应的比较刘俊锋①王翠香①【摘要】目的:比较不同剂量右美托咪定复合罗哌卡因对tbJL骶管阻滞效应的影响,并探讨右美托咪定的合适剂量。方法:选取本院60例1—7岁择期行腹股沟疝修补术或隐睾下降固定术的患儿,按照随机数字表法将其均分为R组、RD1组和RD2组各2O例,R组给予0.25%罗哌卡因1ml/kg,RD1组相同局麻药中加入右美托咪定1IXgg,RD2组加入2s/ks。观察
2、比较三组术中七氟烷维持浓度、苏醒期行为状态评分、苏醒期躁动发生率、术后镇静状态评分、有效镇痛时间、需追加镇痛的比例、睡眠质量、麻醉恢复情况及术后并发症等。结果:与R组比较,RD1组和RD2组的术中七氟烷维持浓度、苏醒期行为状态评分、苏醒期躁动、术后镇静状态评分、有效镇痛时间、需追加镇痛的例数及次数、睡眠质量等比较差异均有统计学意义(P3、差异均无统计学意义(P>O.05)。结论:0.25%罗哌卡因1ml/kg中加入右美托咪定1或2s/ks行小儿骶管阻滞,能明显增强阻滞效果,减少七氟烷用量,减少苏醒期躁动,术后早期维持适度镇静,显著延长术后镇痛时间,提高睡眠质量,且不影响麻醉恢复及增加并发症。与1昏右美托咪定相比,2g/kg不仅同样安全而且效果更好。【关键词】右美托咪定;罗哌卡因;骶管阻滞;4,JLComparisonofDiferentDosesofDexmedetomidineAddedtoRopivacaineontheEfectofCaudalBloc4、kinPediatrics/LIUJun-feng。WANGCui-xiangd/MedicalInnovationofChina,2014。11(16):053-057【Abstract】Objective:Tocomparethediferentdosesofdexmedetomidine(DEX)combinedwithropivacaineontheefectofpediatriccaudalblock,anddeterminethesuitabledosageofDEX.Method:Sixtychildren(A5、SAI)aged1-7yearsscheduledforelectiveinguinalherniarepairororchidopexywererandomlyrandomlydividedintothegroupR,thegroupRD1andthegroupRD2.20casesineachgroup.ThegroupRreceivedacaudalinjectionof0.25%ropivacaine1ml/kg,thegroupRD1receivedthesamedoseofropivacainemixedwith6、DEX1g/kg,andthegroupRD2mixedwithDEX2g,l【g.Theend-tidalsevofluraneconcentration(ET—sevo),emergencebehaviorstatescore,incidenceofemergenceagitation(EA),postoperativesedationscore,durationofpostoperativeanalges.ia,theproportionofrequirementforadditionalanalgesics,qual7、ityofsleep,recoveryfromanesthesiaandpostoperativecomplicationsamongthethreegroupswereobservedandcompared.Result:TheET-sevo,emergencebehaviorstatescore,incidenceofEAandtheproportionofrequirementforadditionalanalgesicsweresignificantlylower,thequalityofsleepwassignif8、icantlybetter,thepostoperativesedationscorewassignificantlyhigherandthedurationofpostoperativeanalgesiawassignificantlylongerinGroupRD1andGroupRD
3、差异均无统计学意义(P>O.05)。结论:0.25%罗哌卡因1ml/kg中加入右美托咪定1或2s/ks行小儿骶管阻滞,能明显增强阻滞效果,减少七氟烷用量,减少苏醒期躁动,术后早期维持适度镇静,显著延长术后镇痛时间,提高睡眠质量,且不影响麻醉恢复及增加并发症。与1昏右美托咪定相比,2g/kg不仅同样安全而且效果更好。【关键词】右美托咪定;罗哌卡因;骶管阻滞;4,JLComparisonofDiferentDosesofDexmedetomidineAddedtoRopivacaineontheEfectofCaudalBloc
4、kinPediatrics/LIUJun-feng。WANGCui-xiangd/MedicalInnovationofChina,2014。11(16):053-057【Abstract】Objective:Tocomparethediferentdosesofdexmedetomidine(DEX)combinedwithropivacaineontheefectofpediatriccaudalblock,anddeterminethesuitabledosageofDEX.Method:Sixtychildren(A
5、SAI)aged1-7yearsscheduledforelectiveinguinalherniarepairororchidopexywererandomlyrandomlydividedintothegroupR,thegroupRD1andthegroupRD2.20casesineachgroup.ThegroupRreceivedacaudalinjectionof0.25%ropivacaine1ml/kg,thegroupRD1receivedthesamedoseofropivacainemixedwith
6、DEX1g/kg,andthegroupRD2mixedwithDEX2g,l【g.Theend-tidalsevofluraneconcentration(ET—sevo),emergencebehaviorstatescore,incidenceofemergenceagitation(EA),postoperativesedationscore,durationofpostoperativeanalges.ia,theproportionofrequirementforadditionalanalgesics,qual
7、ityofsleep,recoveryfromanesthesiaandpostoperativecomplicationsamongthethreegroupswereobservedandcompared.Result:TheET-sevo,emergencebehaviorstatescore,incidenceofEAandtheproportionofrequirementforadditionalanalgesicsweresignificantlylower,thequalityofsleepwassignif
8、icantlybetter,thepostoperativesedationscorewassignificantlyhigherandthedurationofpostoperativeanalgesiawassignificantlylongerinGroupRD1andGroupRD
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