资源描述：
《尼莫地平治疗自发性蛛网膜下腔出血的作用观察.doc》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、尼莫地平治疗自发性蛛网膜下腔出血的作用观察［摘要］目的研究尼莫地平治疗自发性蛛网膜下腔出血的临床疗效。方法选取2013年4月〜2015年3月于我院就诊的自发性蛛网膜下腔出血患者52例，随机分为观察组(常规疗法联合尼莫地平治疗)与对照组(常规治疗)各26例，对比两组的临床治疗效果。结果观察组的头痛、呕吐以及意识模糊等临床症状的消失时I'可分别为(4・68±1.74)d、(2.14±0.55)d、(5.32±2.08)d,均低于对照组，组间对比差异显著(t二12.48,7.60,16.49；1X0.05)。观察组的治疗总有
2、效率为92.31%,显著高于对照组(x2二6.40；P〈0・05)；观察组的出血吸收时间与脑血管痉挛发生率分别为(6.32±1・20)d、1例(3.85%)；均显著低于对照组水平,组间差异具统计学意义(t=9・34,x2=4.12；P<0.05)o结论应用尼莫地平治疗自发性蛛网膜下腔出血的效果优良，可促进症状改善、降低脑血管痉挛发生率，有利于病情康复，值得推广应用。［关键词］尼莫地平；自发性蛛网膜下腔出血；临床疗效［中图分类号］R743.3［文献标识码］B［文章编号］2095-0616(2015)19-127-03［A
3、bstract］ObjectiveTostudytheclinicalcurativeeffectofnimodipineintreatmentofspontaneoussubarachnoidhemorrhage.Methods52patientswithspontaneoussubarachnoidhemorrhagewhowereadmittedtoourhospitalfromApril2013toMarch2015wereselectedandtheywererandomlydividedintotheobs
4、ervationgroup(routinetreatmentcombinedwithnimodipine)andthecontrolgroup(routinetreatment),with26ineach.Clinicalcurativeeffectsoftwogroupswerecompared.ResuItsDisappearedtimeofclinicalsymptomsincludingheadache,vomiting,confusionandsoonoftheobservationgroupwere(4.6
5、8+1.74)d,(2.14+0.55)dand(5.32±2.08)drespectively,lowerthanthoseinthecontrolgroup,Differencesbetweentwogroupsweresignificant(t二12.48,7.60,16.49；卩〈0.05)・Totaleffectiverateoftreatmentintheobservationgroupwas92.31%,significantlyhigherthanthatofthecontrolgroup(x2二6.4
6、0；P〈0.05).Hemorrhageabsorptiontimeandtheincidenceofcerebralvasospasmoftheobservationgroupwere(6.32±1.20)dand1case(3.85%)respectively,bothsignificantlylowerthanthoseinthecontrolgroup.Differencesbetweentwogroupswerestatisticallysignificant(t=9>34,x2二4.12；P<0.05)•C
7、onclusionNimodipineintreatmentofspontaneoussubarachnoidhemorrhagehasgoodcurativeeffect・Itcanpromotetheimprovemeofsymptomsandincidenceofcerebralvasospasmwhichishelpfulfordiseaserehabilitation,worthyofpromotionandapplication.[Keywords]Nimodipine；Subarachnoidhemorr
8、hage；Clinicalcurativeeffect自发性蛛网膜下腔出血患者的常规疗法以脑脊液净化为主，以降低或避免脑血管痉挛的发生风险[1-2],但该种疗法会给患者带来较大痛苦，对主治医师的索质水平也有较高要求，不适于临床推广。为此，本研究通过随机対照试验，分析尼莫地平治疗自发性蛛网膜下腔出血的临床效果，旨在为临床工作提供参考
