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《早期康复介入对急性脑梗死炎症反应的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、中国康复理论与实践2Ol0年9月第16卷第9期ChinJRehabilTheoryPract,Sept.2010,Vo1.16,No.9·807··专题·早期康复介入对急性脑梗死炎症反应的影响甘照儒,石丽华,蔡超群,谢智光,徐英妹,刘海朋,桑栎楠[摘要]目的观察期埭复治疗时急性腑梗死(ACI)患者的运动功能、血清超敏C一反应蛋门(hs—CRP)、n细胞介素l(IL1)和白细胞介素6(II6)含量动态变化的影响。方法160例ACI患肯随机分为两组,康复绀8O例采用早期球复治疗和常规lI】西药物治疗,对照组8O例仪采
2、用常规中约物治疗。测定两患者治疗和治疗后l、2、4、8周后外周血hsCRP、II1和II6含量,用改良爱丁催斯堪的纳维、摘中评定表(MESSS)进行神经功能评定。结果康复组治疗后4、8周时外周『0lhsCRP、II1和IL6水平低于对照组(P3、胞介素一l;细胞介素6;神绎功能EffectofEarlyRehabilitationOilInflammatoryResponseafterAcuteCerebralInfarction(;ANZhaorid.SHILihua.CAlChao—qun,ela1.Departmento/Neurology,RuikangHospitalo,Guang、ri-/、raditionalChineseMedicalUniversity,Nanning530011,Guangxi,ChinaAbstract:Object4、iveToobservetheeffectofearlyrehabilitationonmotorfunction,highsensitivityCreactiveprotein(hsCRP),interleukin一1(II一1)andinterleukin一6(IL一6)inpatientswithacutecerebralinfarction(ACI).Methodsl60patientswithAC1wererandomlydividedintorehabilitationgroup(n一80)andco5、ntrolgroup(n一80),whoacceptedearlyrehabilitationandroutinemedicineormedicineonly,respectively.TheywereassessedwithmodifiedEdinburghScandinavianStrokeScale(MESSS)andtheirperipherallevelofhs—CRP,II一1andII一6weredetectedbeforeand1,2,4,and8weeksaftertreatment.Resul6、ts4and8weeksaf—tertreatment,the1evelofhs—CRP,Ii1andIL6werelowerinrehabIlitationgroupthanincontrolgroup(P<0.05),aswellasthescoresoftheMESSS(P<0.01).rrheincidenceofimprovementismoreinrehabmtationgroupthanincontrolgroup(P<0.05).ConclusionEarlyrehabilitationcanre7、ducetheexpressionofhsCRP,IIlandII6.andimprovetheneurologicalfunctioninpatientswithACI.Keywords:acutecerebralinfarction;earlyrehab_1itati()n;highsensitivityC—reactiveprotein;interleukin1;interleukin6;neurologicalfunction[中图分类号]R743.3[文献标识码]A[文章编号]10069771(2O108、)09080702[本文著录格式]}f‘肌儒,彳丽华,蔡超群,等.崩康复介入财急性腑梗夕匕炎症反应的影响[J].【}J康复沦实践,2O1O,16(9):807808.脑梗死是高发病率及致残率的疾病,尽管近几十肝肾功能严重损害、上消化道大出血、2糖尿病;④年国内外对脑梗死进行了大量研究,但其预后仍相当病程>7d,病情轻,偏瘫肢体肌力>Ⅲ级。差,存活者中50~7O患者遗留瘫痪
3、胞介素一l;细胞介素6;神绎功能EffectofEarlyRehabilitationOilInflammatoryResponseafterAcuteCerebralInfarction(;ANZhaorid.SHILihua.CAlChao—qun,ela1.Departmento/Neurology,RuikangHospitalo,Guang、ri-/、raditionalChineseMedicalUniversity,Nanning530011,Guangxi,ChinaAbstract:Object
4、iveToobservetheeffectofearlyrehabilitationonmotorfunction,highsensitivityCreactiveprotein(hsCRP),interleukin一1(II一1)andinterleukin一6(IL一6)inpatientswithacutecerebralinfarction(ACI).Methodsl60patientswithAC1wererandomlydividedintorehabilitationgroup(n一80)andco
5、ntrolgroup(n一80),whoacceptedearlyrehabilitationandroutinemedicineormedicineonly,respectively.TheywereassessedwithmodifiedEdinburghScandinavianStrokeScale(MESSS)andtheirperipherallevelofhs—CRP,II一1andII一6weredetectedbeforeand1,2,4,and8weeksaftertreatment.Resul
6、ts4and8weeksaf—tertreatment,the1evelofhs—CRP,Ii1andIL6werelowerinrehabIlitationgroupthanincontrolgroup(P<0.05),aswellasthescoresoftheMESSS(P<0.01).rrheincidenceofimprovementismoreinrehabmtationgroupthanincontrolgroup(P<0.05).ConclusionEarlyrehabilitationcanre
7、ducetheexpressionofhsCRP,IIlandII6.andimprovetheneurologicalfunctioninpatientswithACI.Keywords:acutecerebralinfarction;earlyrehab_1itati()n;highsensitivityC—reactiveprotein;interleukin1;interleukin6;neurologicalfunction[中图分类号]R743.3[文献标识码]A[文章编号]10069771(2O10
8、)09080702[本文著录格式]}f‘肌儒,彳丽华,蔡超群,等.崩康复介入财急性腑梗夕匕炎症反应的影响[J].【}J康复沦实践,2O1O,16(9):807808.脑梗死是高发病率及致残率的疾病,尽管近几十肝肾功能严重损害、上消化道大出血、2糖尿病;④年国内外对脑梗死进行了大量研究,但其预后仍相当病程>7d,病情轻,偏瘫肢体肌力>Ⅲ级。差,存活者中50~7O患者遗留瘫痪
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