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时间:2017-12-08
《安全输血采用不规则抗体筛查的临床价值》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、·838·右江医学2013年第41卷第6期YoujiangMedicalJournal2013,Vo1.41No.6安全输血采用不规则抗体筛查的临床价值戎世琴(江苏省海安县人民医院输血科,江苏海安226600)【摘要】目的探讨临床输血前采用不规则抗体筛查对安全输血的临床价值。方法收集2010年1月至2013年5月1839例输血患者,以coombs卡进行不规则抗体筛查,随后进行交叉配血试验,并对结果进行统计学分析。结果1839例患者血清标本中,共检出不规则抗体阳性患者17例(O.92),其中,男性4例,女性13例;不规则抗体阴
2、性1822例(99.08),其中,男性1039例,女性783例。对不规则抗体阳性和阴性患者进行性别比较发现,抗体阳性患者中女性比例高于男性(=7.698,P—O.006);不规则抗体检测,以Rh血型系统为最多,共检测出8例(47.06),其次为MNS血型系统,共3例(17.65%);对不规则抗体阳性患者进行特异性鉴定发现,特异性抗体15例(88.23%),未确定特异性抗体2例(11.77)。结论对患者进行输血前不规则抗体筛查,可防止抗体引起的溶血性输血反应,对临床输血安全意义重大。【关键词】安全输血;不规则抗体筛查;交叉配血
3、;特异性文章编号:1003—1383(2013)06—0838—03中图分类号:R446.6文献标识码:Adoi:10.3969/j.issn.1003~1383.2013.06.O16ClinicalvalueofirregularantibodyscreeninginsafebloodtransfusionRONGShiqin(BloodTransfusionDepartment,Hai’anPeople’SHospital,Hai’n226600,Jiangsu,China)[Abstract]ObjectiveToi
4、nvestigatetheclinicalvalueofirregularantibodyscreeninginsafebloodtransfusionbeforeclinica1bloodtransfusion.MethodsIrregularantibodiesof1839bloodrecipientsfromJan,2010toMay,2012weredetectedbyCoombsMicrotubeGeltestandweregivencrossmatchtest.Theirresultswerestatistica
5、llyaria—lysed.ResultsAftertheserumspecimensofthe1839bloodreceipientsweretested,17(O.92)positivecaseswithirregularantibodieswerefound,including4malesand13females.Andtherest1822(99.08)werenegativecaseswithirregularantibodies,including1039malesand783females.Thegenders
6、tatisticsofpatientswithirregularpositivean—tibodiesandthosewithnegativeantibodiesshowedthatthepositiverateofirregularantibodiesinfemalebloodrecipi—entswashigherthanthatinmale.andthedifferencewasstatisticallysignificant(X:7.689,P—O.006).Inirregularantibodydetection。
7、thecaseswithRhbloodgroupsystemaccountedforthemost(8cases,47.06)andwerefollowedbyMNSbloodgroupsystem(3cases,17.65).Specificidentificationofthepatientswithirregularpositiveantibodyindieatedthattherewere15cases(88.23%)withspecificantibodiesand2cases(11.77%)withuncerta
8、inspecifican—tibodies.ConclusionIrregularantibodyscreeningbeforebloodtransfusioncanpreventthehemolytictransfusionreac—tioncausedbyantibodies,SOit
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