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时间:2017-12-07
《30味中药对人头皮游离毛囊体外培养的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、世界最新医学信息文摘2013年第13卷第20期l5·论著·30昧中药对人头皮游离毛囊体外培养的影响郑罡,王一臣,鲁慧,王琦(东南大学医学院附属徐州医院皮肤科,江苏徐州221009)摘要:目的探讨中草药对人头皮游离毛囊器官体外培养的影响,为医治脱发的新药开发提供新的思路。方法采用体外器官培养法对人头皮游离毛囊进行培养,观察体外培养生长毛囊的形态变化及30味中药对人头皮游离毛囊生长的影响。结果体外培养的人头皮游离毛囊在1—4天生长速度最快,毛囊的形态结构在10天内无明显改变,制首鸟、牛膝、熟地、女贞子、旱莲草、骨碎补、桑寄生、柏子仁等中药对体外培养的人头皮游离毛囊有明显的促生长作用,其中以中药
2、制首乌、牛膝、熟地作用最为明显(户3、vitroZhengGang,WangYi.chen,LUHui,WangQi.(DepartmentofDermatology,TheAflfliatedXuzhouHospital,MedicalCollegeofSoutheastUniversi(g,Xuzbou,221009,Jiangs~China)ABSTRACT:ObjectiveWeinvestigatetheeffectof30Chineseherbalmedicinesinthecultureofhumanhairfollicleinvitro.MethodsAninvitroorganculturemodelofhu4、manhairfolliclewasusedtoinvestigatetheeffect0f30Chineseherbalmedicinesonthelengthofhairgrowthandmorphologicalchangeofthebulb.ResultsTheresultsdemonstratedthatthehairgrowthwassignificantlystimulatedinthefc)lliclesculturedwithPolygonummultiflorum。Achyranthesbidentata.RehmanniaglutinosaLibosch,Ligus~5、rnLncidum,Ecliptaprostrata,Drynariafortunei,TaxilluschinensisorPlatyclatusorientalis<0.05).whereasthehairgrowthwasinhibitiedinfolimesculturedwithVitextrifolia,Cuscutachinensis,Astragalusmembranaceus,Morusalba.StemonasessilifoliaorPoriaCOCOS<0.05).PolygonummultiforumandRadixrehmanniapraeparatestimu6、latedhairgrowthintheculturedependonitsconcentration.ConclusionsThisis也efirststudytodemonstratetheeffectsofChineseherbalmedcinesonhumanhairfolliclecultureinvitro.Resultsfromthisstudyhavefurnishedtheinformationtodevelopnewmedicinesforhairdisorder.KEYWRODS:hairfollicles;cultureinvitro;Chineseherbalme7、dicines0引言2.1毛囊的分离脱发是常见病多发病,其病因与发病机制十分复杂。传参照文献_3的方法分离毛囊,选取完整无损的生长期统中医对于脱发的描述最早见于《黄帝内经》,书中所记载毛囊进行培养。的“毛拔、发落、发坠”等,即指脱发。明代《外科正宗》2.2毛囊器官体外培养2.2.1分别用30味中药对人头皮游离毛囊进行体外培中所载的“油风”一病即相当于现代医学的斑秃。我们从养,实验共使用6块24孔培养板,每板分为6个实验组
3、vitroZhengGang,WangYi.chen,LUHui,WangQi.(DepartmentofDermatology,TheAflfliatedXuzhouHospital,MedicalCollegeofSoutheastUniversi(g,Xuzbou,221009,Jiangs~China)ABSTRACT:ObjectiveWeinvestigatetheeffectof30Chineseherbalmedicinesinthecultureofhumanhairfollicleinvitro.MethodsAninvitroorganculturemodelofhu
4、manhairfolliclewasusedtoinvestigatetheeffect0f30Chineseherbalmedicinesonthelengthofhairgrowthandmorphologicalchangeofthebulb.ResultsTheresultsdemonstratedthatthehairgrowthwassignificantlystimulatedinthefc)lliclesculturedwithPolygonummultiflorum。Achyranthesbidentata.RehmanniaglutinosaLibosch,Ligus~
5、rnLncidum,Ecliptaprostrata,Drynariafortunei,TaxilluschinensisorPlatyclatusorientalis<0.05).whereasthehairgrowthwasinhibitiedinfolimesculturedwithVitextrifolia,Cuscutachinensis,Astragalusmembranaceus,Morusalba.StemonasessilifoliaorPoriaCOCOS<0.05).PolygonummultiforumandRadixrehmanniapraeparatestimu
6、latedhairgrowthintheculturedependonitsconcentration.ConclusionsThisis也efirststudytodemonstratetheeffectsofChineseherbalmedcinesonhumanhairfolliclecultureinvitro.Resultsfromthisstudyhavefurnishedtheinformationtodevelopnewmedicinesforhairdisorder.KEYWRODS:hairfollicles;cultureinvitro;Chineseherbalme
7、dicines0引言2.1毛囊的分离脱发是常见病多发病,其病因与发病机制十分复杂。传参照文献_3的方法分离毛囊,选取完整无损的生长期统中医对于脱发的描述最早见于《黄帝内经》,书中所记载毛囊进行培养。的“毛拔、发落、发坠”等,即指脱发。明代《外科正宗》2.2毛囊器官体外培养2.2.1分别用30味中药对人头皮游离毛囊进行体外培中所载的“油风”一病即相当于现代医学的斑秃。我们从养,实验共使用6块24孔培养板,每板分为6个实验组
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