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1、·1732·中华实用医药杂志ChineseJournalofPracticalMedicine2006年第6卷第19期·论著·中链甘油三酯对糖尿病患者体重和体脂的影响研究1,221Δ孙静,胡志庚,马静【摘要】目的观察中链甘油三酯(MCT)干预对2型糖尿病(T2DM)患者体重和体脂的影响。方法将糖尿病患者分为MCT组、MCT/LCT组和LCT组,在接受食物交换份法的膳食宣教、总能量和脂肪摄入量得到控制的基础上,每天分别食用不同组成的食用油30ml,连续食用12周。在0和12周时进行膳食调查和评价。在0、6周和12周时测
2、量空腹血糖、β-羟基丁酸、身高、体重、腰围和臀围,计算体质指数(BMI)和腰臀比(WHR)。结果在12周时MCT/LCT组摄取的总能量、蛋白质量和脂肪量比LCT组低,MCT/LCT组摄取的脂肪量也比MCT组低。在0、6和12周时,3组的空腹血糖和β-羟基丁酸差异均无显著性。相比LCT组,6周和12周时MCT组和MCT/LCT组的体重、BMI均较低,腰围也明显较小。12周时MCT组的WHR明显小于LCT组的WHR。结论在总能量和脂肪摄入量得到控制的基础上,用MCT取代100%或50%的膳食油脂,具有降低T2DM体重、腰
3、围和腰臀比的减肥作用,对患者的空腹血糖和β-羟基丁酸没有影响。【关键词】MCT;2型糖尿病;肥胖;体重;BMI;WHR【中图分类号】R58711【文献标识码】A【文章编号】1606-8106(2006)19-1732-05TheeffectsofMCTonobesityintype2diabetesSUNJing,HUZhi-geng,MAJing1DepartmentofNutrition,SchodofPublicHealth,SunYat-senUniverstiy,Guangzhou510089,China【
4、Abstract】ObjectiveToobservetheeffectsofMCTonbodyweightandbodyfatintype2diabetics.MethodsT2DMsweredividedintoMCTgroup,MCT/LCTgroupandLCTgroup.Withtotalenergyandfatconsumptioncontrolled,theyweregivendifferentproportiontestoilafterreceivingeducationoffoodcrossover
5、method.Allpa2tientsweretoldtotakethetestoileverydayfor12weeks.Wediddietsurveyandevaluationduring0and12wk.Wealsodetectedfastingplasmaglucose(FPG),β-hydroxybutyricacid(BHBA)andmeasuredbodyheight,bodyweight,waistlineandhiplineat0wk,6wkand12wk.ThenBMIandWHRwereanal
6、yzed.ResultsComparedwithLCTgroup,totalenergy,proteinandfatconsumptioninMCT/LCTgroupweredecreased.MCT/LCTgroupalsohadlesserfatconsumptionthanMCTgroup.TherewerenosignificantdifferencesonFPGandBHBAamongthreegroups.ComparedwithLCTgroup,bodyweight,BMIandwaistlineof6
7、wkand12wkinMCTandMCT/LCTgroupsweredecreasedandWHRof12wkinMCTgroupwasmuchdecreased.ConclusionWithtotalenergyandfatconsumptioncontrolled,thedailydietoilisreplacedfullorpartlybyMCT,thebodyweight,BMIandWHRdecreaseonT2DMpatients,implicatingthatMCThelpstopreventobesi
8、ty.NoinfluenceforFPGandβHBAlevelonT2DM1【Keywords】MCT;T2DMobesity;bodyweight;BMI;WHR2型糖尿病(T2DM)患者通常比非糖尿病者具收、直接通过门静脉转运至肝脏并且不依赖肉毒碱有更高的体重,减轻体重可降低T2DM发生冠心病就可直接迅速进行β氧化,不易造成脂肪储存,可[
