自噬及其与肿瘤关系的研究进展.pdf

《自噬及其与肿瘤关系的研究进展.pdf》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、现代肿瘤医学2010年6月第18卷第6期·1247·ofB－cellchroniclymphocyticleukemiacells［J］．Leukemia，establishanovelmicroRNAprofileofchroniclymphocyticleuke-2008，22(3):585－592．mia［J］．Blood，2007，109(11):4944－4951．［32］BenedettiD，BombenR，Dal－BoM，etal．Aresurrogatesof［36］MartonS，GarciaMR，RobelloC，etal．SmallRN

2、AsanalysisinIGHVgenemutationalstatususefulinB－cellchroniclymphocyt-CLLrevealsaderegulationofmiRNAexpressionandnovelmiR-icleukemia?TheexampleofSeptin－10［J］．Leukemia，2008，22NAcandidatesofputativerelevanceinCLLpathogenesis［J］．(1):224－226．Leukemia，2008，22(2):330－338．［33］HeintelD，Kroeme

3、rE，KienleD，etal．Highexpressionofacti-［37］GatteiV，BulianP，DelPrincipeMI，etal．RelevanceofCD49dvation－inducedcytidinedeaminase(AID)mRNAisassociatedproteinexpressionasoverallsurvivalandprogressivediseaseprog-withunmutatedIgVHgenestatusandunfavourablecytogeneticab-nosticatorinchroniclym

4、phocyticleukemia［J］．Blood，2008，111errationsinpatientswithchroniclymphocyticleukaemia［J］．(2):865－873．Leukemia，2004，18(4):756－762．［38］ShanafeltTD，GeyerSM，BoneND，etal．CD49dexpressionis［34］BuhlAM，JurlanderJ，GeislerCH，etal．CLLU1expressionlev-anindependentpredictorofoverallsurvivalinpati

5、entswithchron-elspredicttimetoinitiationoftherapyandoverallsurvivaliniclymphocyticleukaemia:aprognosticparameterwiththerapeuticchroniclymphocyticleukemia［J］．EurJHaematol，2006，76potential［J］．BrJHaematol，2008，140(5):537－546．(3):455－464．(编校:何姝)［35］FulciV，ChiarettiS，GoldoniM，etal．Quant

6、itativetechnologies自噬及其与肿瘤关系的研究进展郭德玉，孙慧勤ProgressioninthestudyofautophagyanditsrelationtocancerGUODe－yu，SUNHui－qinDepartmentofPathology，SouthwestHospital，ThirdMilitaryMedicalUniversity，Chongqing400038，China．【Abstract】Autophagyisanessentialvitalphenomenaineukaryocyte．Itisveryimportan

7、tinmaintaininghomeostasisandviabilityofcells．Autophagyexistswidelyinphysiologicalandpathologicalprocesses．Thereisacloserelation-shipbetweenautophagyandtumorcellsurvivalanddeath．Itprovidesusapromisingavenueforcancertherapyandprevention．Thisreviewfocusesonthecharacteristicsofautophag

8、yanditsrelationshipwithcan