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1、前列地尔联合倍他司汀治疗椎-基底动脉供血不足的临床疗效胡叶丽南方医科大学深圳医院神经内科摘要：冃的探讨前列地尔联合倍他司汀治疗椎-基底动脉供血不足的临床疗效。方法随机选取南方医科大学深圳医院2016年1月至2017年5月期间收治的椎-基底动脉供血不足患者，抽取80例纳入研究，用随机数字法分两组，各40例。对照组患者接受前列地尔药物治疗，研究组患者接受倍他司汀联合前列地尔药物治疗，观察两组患者的治疗状况、血流速度等，并对比分析。结果研究组治疗总疗效为92.5%,高于对照组的72.5%,组间数据差异有统计学意义(P<0.05)。对比两
2、组患者血流速度，治疗前组间数据比较差异无统计学意义(P>0.05),治疗后研究组高于对照组，差异有统计学意义(P<0.05);对比两组患者纤维蛋白原、D-二聚体，治疗前组间数据比较差异无统计学意义(P>0.05)，治疗后研究组低于对照组，差异有统计学意义(P<0.05);对比血脂指数，包含IIDL-C、LDL-C、TG、TC等，治疗前组间数据比较差异无统计学意义(P>0.05),治疗后研究组各指标均优于对照组，差异均有统计学意义(均P<0.05)。结论临床治疗椎-基底动脉供血不足患者可以考虑给予前列地尔联合倍他司汀药物治疗，其疗效
3、突出，能明显改善纤维蛋白原、D-二聚体以及血脂指数。关键词：椎-某底动脉供血不足;前列地尔;倍他司汀;疗效;血流速度;作者简介：胡叶丽(1988.9-),本科学历。研究方向:脑梗塞眩晕。E-mai1:304899852@qq.comAnalysisofclinicaleffectofAlprostadilcombinedwithduloxetineintreatmentofvertebrobasilarinsufficiencyHuYeliAbstract：ObjectiveToanalyzeanddiscusstheclinic
4、aleffectsofAlprostadi1combinedwithduloxetineintreatmentofvertebrobasilar.Methods80casesofpatientswithvertebrobasilarinsufficiencyandwhoacceptedtreatmentsinShenzhenHospitalofSouthernMedicalUniversityfromJanuary,2016toMay,2017wererandomlyselectedandincludedinthediscussi
5、on,andwererandomlydividedintotwogroups,with40casesineachgroup.Thecontrolgroupwerereceivedtheduloxetinetreatment,whilethestudygroupweretreatedwithAlprostad订combinedwithalprostadi1.Then,thetreatmentconditionandbloodflowvelocitywereobservedandcompared.ResultsThetotalclin
6、icaleffectinthestudygroupwas92.5%,whichwashigherthanthatinthecontrolgroupof72.5%,andthedatabetweenthetwogroupswerestatisticallysignificant(P<0.05).Themeanvelocityofthevertebrobasilararterywerecomparedbetweenthetwogroups,andtherewasnosignificantdifferencebetweenthetwog
7、roupsbeforetreatment(P〉0.05);Afterthetreatment,thestudygroupwashigherthanthecontrolgroup,thedateibetweenthetwogroupswerestatisticallysignificant(P〈0・05).ThefibrinogenandD-dimeroftwogroupsofpatientswerecompared.Therewasnosignificantdifferencebetweenthetwogroupsbeforetr
8、eatment(P>0.05);Afterthetreatment,thestudygroupwaslowerthanthecontrolgroup,thedatabetweenthetwogroupswerestatisticallysignif
