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1、S385.Microbiology149*2009H1N1influenzaAincysticfibrosispatients.AFrench151*Sino-pulmonarypairsofmucoidandnon-mucoidPseudomonascollaborativestudyaeruginosaisolatesfromcysticfibrosispatientswithchronicJ.Bucher1,D.Hubert2,G.Bellon3,E.Deneuville4,B.Delaisi5
2、,H.Corvol6,airwaysinfectionhavesimilargeneexpressionprofilesV.Boussaud7,F.Bremont8,M.Ramadour1,I.Petit9,M.Renouil10,M.V.Vodoff11,121121O.Ciofu,H.K.Johansen,T.Wassermann,M.Alhede,N.Høiby.UniversityF.Troussier12,C.Vallier1,N.Remus13,L.Bassinet14,D.Grene
3、t15,M.Leruez1,O.Launay2,O.Lortholary1,I.Sermet-Gaudelus1.1HopitalNecker,Paris,France;ˆofCopenhagen,InternationalHealth,ImmunologyandMicrobiology,Copenhagen,23Denmark;2UniversityHospitalRigshospitalet,ClinicalMicrobiology,Copenhagen,HopitalCochin,APHP
4、,Paris,France;ˆHospicescivilsdeLyon,Lyon,France;4HopitaldeRennes,Rennes,France;ˆ5HopitalCochin,APHPRobertDebrˆe,APHP,´DenmarkParis,France;6HopitalTrousseau,APHP,Paris,France;ˆ7HopitalGeorgesPompidou,ˆSino-nasalinvolvementinCFhasbeenproposedasagateway
5、andreservoirParis,France;8HopitauxdeToulouse,Toulouse,France;ˆ9HopitauxdeClermontˆforpulmonaryinfectionwithP.aeruginosa.Mucoid(M)andnon-mucoid(NM)Ferrand,ClermontFerrand,France;10HopitaldesaintPierre,SaintPierre,France;ˆ11HopitaldeMulhouse,Mulhouse,F
6、rance;ˆ12HopitalNecker,Paris,France;ˆ13CHIC,P.aeruginosaisolatesfromsinusesandlungshavebeenphenotypicallyandCreteil,France;´14CHIC,Creteil,France;15HopitalFoch,Suresnes,Franceˆgenotypicallycharacterizedinordertorevealadaptivemechanismsspecifictothetwo
7、compartmentsofthe“unitedairways”.Background:InfluenzaviruseshavebeenshowntocausediseaseprogressioninCysticTwenty-threeP.aeruginosaisolatesrepresentingMandNMpairsfromsinusandFibrosis(CF).Theaimofthisstudywastodocumenttheinfluenceofthepandemiclungfrom6ch
8、ronicallyinfectedCFpatientswereincludedinthestudy.TheH1N1influenzaA2009(H1N1/09)outbreakontheoutcomeofCFpatients.isolateswereobtainedbyFunctionalEndoscopicSinusSurgeryandfromsputumMethods:12FrenchCFcenterscontributedretrospectiveandprospectivedatafors
