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1、J.Vet.Med.B36,131-133(1989)01989PaulPareyScientificPublishers,BerlinandHamburgISSN0931-1793InrtitutodeMicrobiologia,FacultaddeCiencias,UniversidadAustraldeChileCoronavirusasAgentofNeonatalCalfDiarrheainSouthernChile"G.REINHARDT,S.RIEDEMANN,M.POLEITEandM.NIEDDAAddressofauthors:Casilla567,Valdivia
2、,ChileWithonefigure(ReceivedforpublicationAugust3,1988)SummaryNeonatalcalfdiarrheaisoneofthemostseriousproblemsofcattleindustryallovertheworld.Althoughtheaetiologyiscomplex,itispossibletoassessthatvirusesplayaveryimportantrole.DuringaninvestigationtostudytheimportanceofRotavirusinentericproblems
3、incalvesandpiglets,itwaspossibletodemonstratethepresence,forthefirsttimeinsouthernChile,ofCoronavirus-likeparticlesinafaecalsampleofa15daysoldcalfbymeansofelectronmicroscopy.Theimportanceofthisdiagnosisandsomeclinicalcharacteristicsofthediseasearebrieflydiscussed.Finally,theneedformoreresearchon
4、thiscomplexsubjectisrecognized.Keywords:Neonataldiarrhea,viralinfection,calfIntroductionAsthesystemsofcalfbreedinghaveintensified,amarkedincreaseinneonataldiarrheahasbeenobserved.Theeconomiclossesarehighandmainlyduetoadeficientgrowthoftheaffectedanimals,ahighmortalityonsomefarmsandtheexpenseofth
5、erequiredtreatment.Theaetiologyofneonataldiarrheaisdiverse.Besidesinfectiousagents,otherexoge-nonsandendogenonsfactorsparticipateinthegenesisofthedisease,suchasunbalancedfeeding,poorconditions,housing,temperature,transportationandovercrowding(2).Infectiousagentsofneonataldiarrheaincludebacteria,
6、fungi,virusesandparasiteswhichcanactseparatelyor,asoftenisthecase,inacpmbinedform(7,13).Amongtheviralagentsofimportancedescribedhavebeen:BovineViralDiarrhea(BVD)virus,Enterovirus,Parvovirus,Adenovirus,Rotavirus,CoronavirusandAstrovirus(2,3,7,12).InChile,theparticipationofRotavirus(1)andBVD(10)in
7、diarrheicproblemshasbeenreported.Thepresentcommunicationreports,forthefirsttimeinSouthernChile,theparticipationofCoronavirusasanaetiologicalagentofneonatalcalfdiarrhea.')SupportedinpartbyFONDECYT,ProjectN"0163/84.U.S.Copyrig
