冠状病毒Coronavirusl论文-2007 Serological Prevalence of Canine Respiratory Coronavirus in Southern Italy and Epidemiological Relationship with Ca.pdf

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1、JVetDiagnInvest19:176180(2007)BRIEFCOMMUNICATIONSSerologicalprevalenceofcaninerespiratorycoronavirusinsouthernItalyandepidemiologicalrelationshipwithcanineentericcoronavirus1SimonLawrencePriestnall,AnnamariaPratelli,JoeBrownlie,KerstinErlesAbstract.Caninerespiratorycoronavirus(CRCoV)hasbeendetec

2、tedindogssufferingfromrespiratorydiseaseandisthoughttobeinvolvedincanineinfectiousrespiratorydisease(CIRD)complex.Canineentericcoronavirus(CECoV)isawidespreadpathogenofdogs,responsibleformildtoseverediarrheainpups.ThepurposeofthisstudywastoestablishtheseroprevalenceofCRCoVinItalyanditsrelationsh

3、iptoCECoVtypeIIseroprevalence.Theageandyearofsamplecollectionfromseropositivedogswasalsoassessed.Ofadultdomesticdogs,23.3%hadantibodiestoCRCoV,comparedwith86.1%withantibodiestoCECoV.Amongstapopulationofkenneledpups,4.0%hadantibodiestoCRCoV,and97.0%hadantibodiestoCECoV.Keywords:Coronavirus;dogs;e

4、nteric;kennelcough;respiratory.

5、./author-grp[1]/dept-list)>Caninerespiratorycoronavirus(CRCoV)hasbeenintheRepublicofIreland,and17.8%inJapan.11,18TheidentifiedintherespiratorytractofdogsfromalargeseroprevalencerateofCRCoVhasbeenshowntoincre

6、asehumane-adoptionfacilitywithahighprevalenceofcaninewithageinbothUKandUScaninepopulationsandtodeclinefollowingaplateauphasebetween2and11years.18infectiousrespiratorydisease(CIRD).Ithasbeenhypoth-esizedthatCRCoVmayhavearoleincaninerespiratoryTheothercoronavirusofdogs,canineentericcorona-disease.

7、9CIRDisacommoncontagiousdiseasecharacter-virus(CECoV)isknowntobewidespreadinthedogizedbyacuteonsetofadry,hackingandparoxysmalpopulation.CECoVisdividedinto2genotypes:CECoVcough.Thediseaseisoftenmildandrecoveryrapid;typeIisgeneticallysimilartofelinecoronavirus(FCoV)typeIandCECoVtypeIItoFCoVtypeII.

8、16Antibodieshowever,insomecasesinterstitialpneumoniaorseverebronchopneumoniadevelopandcanbefatal.1Anumberofhavebeendetectedin54%ofapopulationofhealthyanddiarrheicpetdogsintheUnitedKingdom,19whileCECoVpathogenshavebeenassocia