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1、ArchivesofVirologyArchivesofVirology55,25--38(1977)©bySpringer-Verlagt977"Runde"Virus,aCoronavirus-LikeAgentAssoeiatedWithSeabirdsandTieksByT.TRAAVlK,R.MEEL,andELISABETt[KJELDSBERGVirusDepartmentAandEnvironmentalToxicologyDepartment,NationalInstituteofPublicHealth,Osl
2、o,NorwayWith5FiguresAcceptedMarch8,1977SummaryFrom2061.uriaecollectedintheseabirdcoloniesatRunde,Norway,twoidenticalvirusstrainsdemonstratingnoantigenicrelationshipstomajorarbo-virusgroupswereisolated.Thenewstrainsdemonstratedacorona-viruslikemorphology,haemagglutinat
3、edchickenredcellsandweresensitivetosodiumdesoxycholate.MultiplicationwithCPEwasdemonstratedinBHK21/c13andBSCdcells,andwithoutCPEinVeroandGMKcellcultures.Themousepatho-genicitywasrelative]ylow.Ingelprecipitationthreetofivespecificlineswereseen.Precipitatingantibodiesha
4、vebeenfoundinseabirdspeciescommonlyin-festedbyI.uriae.TheecologicalcircumstancesoftheisolatesindicateanearlierunrecognizedarboviruscirculatingbetweenseabirdsandI.uriae.Thiscorona-likevirushasbeententativelytermedRundevirus.ImroduetionIn1973investigationswereundertaken
5、toevaluatetheextent,distributionandecologicalcircumstancesofarboviruslociinNorway.Untilthen.,noarbo-virusisolateshadbeenreportedfromthiscountry,althoughecologicalandcli-nicaI/epidemiologicalconsiderations(3,24,26)andalimitedserologicalsurveyonbovinesera(28)indicatedth
6、eexistenceofCentral-Europeantick-borneencephalitisvirusfool.Theearlyphaseoftheprojectconcernsthestudyoftheimportanceofticksasvectors;later,mosquito-borneagentswillbeinvestigated.InNorwayfiveIxodesspeciesareabundant:_[.ricinus(23),I.tria.nguticeps(24),I.hexagonus(17),I
7、.tividus(16)and1.uriae(15,23).ThelatterspeciesispresentatgreatnumbersinthevastNorwegianseabirdcolonies.Itsabilityto26T.TRAAVIK,1:~.MEttL,andELISABETHKJELDSBERG:attackmanandmammMshasbeenquestionable,butthishasbeenrecentlydocumented(18).ThispaperdescribesstudieswithIxod
8、esuriaeasapossiblevector.Thesestudieswereundertakensince:a)Thetickispartofratherconfinedecosystemwhichmightbesuitableforstud
