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1、GASTKOENTEROLOGY1984:87:386-91InfluenceofCoronavirus(TransmissibleGastroenteritis)InfectiononJejunalMyoelectricalActivityoftheNeonatalPigCOLINF.BURROWSandA.M.MERRITTDepartmentofMedicalSciences,CollegeofVeterinaryMedicine.UniversityofFlorida.Gainesville,FloridaFoursilver-silverchlor
2、ideelectrodesweresurgical-wellasashorteningofphase2onthesecondandlyimplantedats-cmintervalsonthejejunalserosathirddayspostinfection.Changesinmyoelectricalof7neonatalpigs.Dailyrecordings,7hinduration,activitywerenotsolelyduetodecreasesinfoodweremadefromeachpigletbeginning3daysafteri
3、ntake,asabnormalitiespersistedwhenfoodintakesurgery.Characteristicmigratingmotilitycomplexesreturnedtonormalonpostinfectionday3,andandshort,distinct(2.5-5.0s),rapidlyaboralmigrat-disruptionoftheactivityfrontandmigratingmoGJ-ingburstsofintensespikeactivity(“migratingac-itycomplexdur
4、ationwerepurelytransmissible-tionpotentialcomplexes”)wereseeninallpreinfec-gastroenteritis-virus-inducedphenomena.Thesetionrecordings.Pigletswereinoculatedwithal-mlfindingssuggestthatinfectionwithtransmissibleoraldoseofa0.1%gutsuspensionfromcoronavirusgastroenteritisvirusdisruptsor
5、ganizedpropulsive(transmissiblegastroenteritis)infectedpigs.Thisre-activityinthejejunumoftheneonatalpig.sultedininappetence,vomiting,anddiarrhea,mostmarkedontheseconddaypostinfection,butwhichThereisincreasinginterestintheeffectsofvarioushadabatedbythethirdday.Whencomparedtoenteropa
6、thogensonintestinalmotility,aswellasinrecordingsfrombothfedandfastednoninfectedtheinterrelationshipsbetweenmotility,absorption,(control)animals,infectionsignificantlyalteredje-andsecretionintheetiopathogenesisofdiarrhea(1).junalmyoelectricalactivityby(a)shorteningtheMoststudiesofth
7、eeffectofentericenteropathogensdurationofthemigratingmotilitycomplexonday1onsmallintestinalmotilityhavebeenconductedbypostinfectionandprolongingitonday2,(b)increas-Mathiasandcoworkers.Usingananesthetizedrabbitingthenumberofabnormalactivityfronts,and(c)model,theseinvestigatorshavesh
8、ownthatbacterialdecreasing
