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1、咼尿酸血症与急性脳梗死的关系临床研究【摘要】目的：探讨高尿酸血症与急性脑梗死发生、发展的相关性。方法：选取2013年9月-2014年9月期间本院诊治的120例急性脑梗死患者，根据空腹血清尿酸水平，将其分为高尿酸血症组（急性脑梗死伴高尿酸血症患者，40例）和正常尿酸组（血清尿酸水平止常的急性脑梗死患者,80例），根据1995年脑卒中临床神经功能缺损程度评分标准，观察和比较治疗前两组中重型、轻型神经功能缺损程度比率、伴发疾病发生率以及治疗后两组临床疗效。结果：治疗前高尿酸血症组中重型神经功能缺损发生率明显高于正常尿酸组，轻型神经功能缺损发生率低于正常尿酸组，两组比较差异均有统计学意义（P〈0
2、.05）；治疗前高尿酸血症组患者伴发疾病（肥胖、高血压、糖耐量异常、高脂血症）的发生率高于正常尿酸组，高尿酸血症组治疗后的总有效率低于正常尿酸组，两组比较差异均有统计学意义（卩〈0.05）。结论：高尿酸血症与急性脑梗死患者的病情进展呈相关性，是预后不良的重要预测因素。【关键词】高尿酸血症；急性脑梗死；相关性TheClinicalResearchoftheRelationshipbetweenHighUricAcidHematicDiseaseandAcuteCerebralinfarction/GUOJian-jun,NTXiao-jun,SHILi,etal.//MedicalInno
3、vationofChina,2015,12（26）：051-053[Abstract]Objective：Todiscusstherelevanceofoccurrenceanddevelopmentwithhighuricacidhematicdiseaseandacutecerebralinfarction.Method:120patientswithacutecerebralinfarctioninourhospitalwereselectedfromSeptember2013toSeptember2014,accordingtothefastingserumuricacidlev
4、el，theyweredividedintohighuricacidhematicdiseasegroup(acutecerebralinfarctionpatientswithhighuricacidhematicdisease,40cases)andnormaluricacidgroup(acutecerebralinfarctionpatientswithnormalserumuricacidlevel,80cases),accordingtoa1995cerebralapoplexyclinicalnervefunctiondefectdegreegradingstandard,
5、thenervefunctiondefectratioofmoderateandseveredegreeandlightdegreebeforetreatment,concomitantdiseaseincidenceandclinicalcurativeeffectaftertreatmentoftwogroupswereobservedandcompared.Result：Beforetreatment,moderateandseveredegreenervefunctiondefectratioofhighuricacidhematicdiseasegroupwashigherth
6、annormaluricacidgroup,lightdegreenervefunctiondefect,ratioofhighuricacidhematicdiseasegroupwaslowerthannormaluricacidgroup,thedifferenceswerestatisticallysignificant(P〈0.05)•Beforetreatment,obesity,theincidenceofhighbloodpressure,abnormalglucosetoleranceandhyperlipidemiainhighuricacidhematicdisea
7、segroupwerehigherthannormaluricacidgroup,thedifferenceswerestatisticallysignificant(P<0.05)•Aftertreatment,thetotaleffectiveraleofhighuricacidhematicdiseasegroupwas1owerthannormaluricacidgroup,thedifferencewasstatistic
