高尿酸血症与代谢综合征各组分关系的临床研究

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1、高尿酸血症与代谢综合征各组分关系的临床研究2011年7月第8卷第20期?临床研究?高尿酸血症与代谢综合征各组分关系的临床研究林丹,郑禄城,许晓玲.1.汕头大学医学院第一附属医院内分泌科,广东汕头515041;2.汕头潮南民生医院内二科,广东汕头515144I摘要]目的:探讨高尿酸血症与代谢综合征各组分的关系.方法:严格筛选我院内分泌科门诊进行糖尿病筛查的1000例作为研究对象,其中代谢综合征患者258例为观察组,无代谢综合征742例为对照组,对两组人群的血糖,血压,胆固醇,三酰甘油,高密度脂蛋白,血尿酸及身高,体重,腰围进行测定,并进行比较分析.结果:观察组血糖,血压,

2、胆固醇,三酰甘油及腰围,体重指数均显着高于对照组,且高血尿酸组各项指标均明显高于血尿酸正常人群.且无论有无代谢综合征,男性血尿酸水平明显高于女性,差异均有统计学意义(P<0.05).结论:高尿酸血症与代谢综合征各组分关系密切,可通过监测血尿酸水平为心脑血管疾病的早期防治和预测提供重要的理论依据.【关键词】高尿酸血症;代谢综合征;高血压;糖尿病【中图分类号】R589【文献标识码】B【文章编号】1673—7212(2011)O7(b卜085—03Theclinicalresearchoftherelationshipbetweenhighuricacidhematic

3、dis.easeandmetabolicsyndromevariouscomponentsL/NDan1ZHENGLuche,XUXiaoling21.TheFirstAffiliatedHospitalofShantouUniversityMedicalCollege,Shantou515041,China;2.DepartmentofIn—ternalMedicineⅡ,ShantouChaonanMingshengHospital,Shantou515144,China)[Abstract]Objective:Tostudytherelationshipbetwe

4、enhi【ghuricacidhematicdiseaseandthemetabolicsyndromevari-OUScomponents.Methods:Tochoose1000peoplewhotookdiabetesscreeningintheendocrinedepartmentofourhospi—talstrictastheresearchobject,ofwhich258peoplewithmetabolicsyndromeastheobservationgroup,742caseswithoutmetabolicsyndromeascontrolgro

5、up,tomeasureandcomparethebloodglucose',bloodpressure,cholesterol,triglycerides,high-densitylipoproteincholesterol,blooduricacidandheight,weightwaistlineofthetwogroups.Results:Thebloodglucose,bloodpressure,cholesterol,triglycerideswaistcircumferenceandbodymassindexoftheobservationgroupwer

6、esignificantlyhigherthanthoseinthecontrolgroup,andtheindicatorsofthegroupofhighblooduricacidweresignificant-lyhigherthanthegroupwithnormalblooduricacid,andwithorwithoutmetabolicsyndrome,theblooduricacidlevelofthemaleweresignificantlyhigherthanwomen,thedifferencewasstatisticallysignifican

7、(P<O.05).Conclusion:Therela—tionshipofhighuricacidhematicdiseaseandtheeachcompositionofmetabolicsyndromewereclose,bymonitoringtheblooduricacidlevelcouldprovideimportanttheorybasisforcardiovasculardiseasepreventionandcontrolandearlyfore—cast.[Keywords]Highuricacidhemati