TCT联合阴道镜在农村妇女宫颈癌普查中的应用.pdf

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1、系例A#SOOCHOWUNIVERSITYTCT联合阴道镜在农村妇女宫颈癌普查中的应用中文摘要TCT联合阴道镜在农村妇女宫颈癌普查中的应用中文摘要目的：探讨宫颈液基薄层细胞学检测（TCT）联合阴道镜下病理组织学检查在农村妇女宫颈癌普查中的临床应用价值。方法：收集本院2013年5月至2014年5月35岁-64岁农村妇女病普查中4099例普查者。分为A组、B组。A组2056例普查者采取TCT联合传统四点活检筛查方法。B组2043例普查者采取TCT联合阴道镜下活检方法。A组筛查出57例TCT细胞学阳性患者，检出率2.77%，采取传统四点活检。组织病理学显示CINI级及以上者16例，占2

2、8.07%。其中CINI级8例，占14.03%，CINII级5例，占8.77%，CINIII级3例，占5.26%。B组筛查出47例TCT细胞学阳性患者，检出率2.30%。采取阴道镜下活检，组织病理学显示CINI级及以上者22例，占46.81%。其中CINI级10例，占21.28%，CINII级6例，占12.77%，CINIII级4例，占8.51%，宫颈鳞癌2例，占4.26%。结果：两组宫颈细胞学阳性检出率差异无统计学意义（P>0.05）；TCT联合阴道镜下的活组织学检查与常规四点活检法相比较后可显示：宫颈癌前病变及宫颈癌的检出率明显提高，比较有显著性差异(P<0.05)结论：宫颈

3、液基薄层细胞学检测（TCT）联合阴道镜下的组织病理学检查，在农村妇女宫颈癌普查中可提高宫颈癌前病变及宫颈癌阳性检出率，适用于农村妇女宫颈癌及癌前病变的普查中。关键词：液基薄层细胞学，阴道镜，组织病理学，宫颈癌作者：邹娟指导老师：陈友国IAbstractApplicationofTCTcombinedwithVaginoscopyinruralwomen'scervicalcarcinomascreeningApplicationofTCTcombinedwithVaginoscopyinruralwomen'scervicalcarcinomascreeningAbstractO

4、bjective:ToinvestigatetheclinicalapplicationvalueofThinprepCytologicTest(TCT)combinedwithhistopathologicalexaminationundervaginoscopyinthecervicalcarcinomascreeningofruralwomen。Methods:Atotalof4099ruralwomenaged35-64yearsfromMay2013toMay2014werecollected.ThewomenweredividedintogroupAandgroupB

5、.The2056womeningroupAwerereceivedTCTcombinedwithtraditionalfourspotsbiopsy.Andthe2043womeningroupBwerereceivedTCTcombinedwithbiopsyundervaginoscopy.57womeningroupAwerediagnosedaspositivecytological.Thediagnosisratewas2.77%.Thewomenwithpositivecytoloicalresultswerethenexaminedbytraditionalfour

6、spotsbiopsy.16caseswereabnormal,accountedfor28.07%.Amongthem,8caseswereCINI(14.04%),5caseswereCINII(8.77%),3caseswereCINIII(5.26%).47womeningroupBwerediagnosedaspositivecytological.Thediagnosisratewas2.30%.Thewomenwithpositivecytoloicalresultswerethenexaminedbyvaginoscopyandfinallydiagnosedby

7、histopathology.22caseswereabnormal,accountedfor46.81%.Amongthem,10caseswereCINI(21.28%),6caseswereCINII(12.77%),4caseswereCINIII(8.51%),2caseswereCervicalsquamouscellcarcinoma.Results:Nodifferencesshowdinthecervicalpositivecytoloicaldetection