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时间:2020-03-01
《PET/CT对合并肺不张非小细胞肺癌治疗方案制定和放疗靶区勾画的影响.doc》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、中佯核医学与分子影橡杂志2012年4月第32巒第2期ChinJ/udM如MolImaidng,Apr.2012,Vol.32,&•2•临床研究•PET/CT对合并肺不张非小细胞肺癌治疗方案制定和放疗靶区勾画的影响王天禄宋颖秋龙军蔡峰姚雷李亚明李光【播要】目的观ftPET/CT对合并肺不张NSCLC治疗方案制定和放疗靶区勾画的影响°方法对拟行粮治性3D-CRT的36例伴有不同程度肺不张的NSCLC患音行PET/CT扫描,視察PET/CT对苴临床分期的影响.及由此带来的治疗方案的改变;再以CT图像和PET/CT融合图像分别勾画靶区•
2、对两者进行比较。结果PET/CT使18例(50.0%.18/36)患者的临床分期发生改变。11例(30.6%,11/36)RPET/CT发现远处转移•临床分期升为IV期,从而更改了治疗方案,其中3例由根治性敢疗改为姑息性放疗,7例由放疗改为化疗,1例转为最佳支持泊疗。25例行帳治性3D-CKT的患祥中,21例放疗靶区均有不同程度改变•其中杷区增九7例,减小12例,靶区位JT移动2例;3例念者庄3IKCRT的旌础上遇加锁骨上区常规放疗。3例姑息性放疗患者中・2例乾区减小」例靶区增大。结论PET/CT通过提高合并肺不张的NSCLC临
3、床分期的准确性.稱助制定更加台理的治疗方案;通过有效检测出区域转穆灶和转移満巴结•降低把区遗Si的可能;较CT更准确区分肿网与不张肺组织,提高了杷区勾画的准确性■【关键词】癌■非小细胞肺;肺不张;体层摄影术,发射型计算机;体层摄影术,X线计算机;放射疗法;脱ImpactofPET/CTonthetreatmentplanningandtargetvolumedelineationofradiotherapyinthepatientswithnon-smalbcelllungcancercomplicatedbyatelectas
4、isWANGTian-lu'.SONGYing-qiutDANGJun.CAIFengYAOUn.UYa-mitig^IJGuang.9LkpartmentofRadiotherapyfLiaoningCancerHospitalandInstitutetShenyang110042^ChinaCorrespondingauthor:UCuang.Email:liguangl963@yahoo,com.cn(Abstract]ObjectiveToinveBti^aietheimpactofPET/CTonthetrealmen
5、lplanningandtargetvolumedelineationofradioihentpyinpatientswithNSCLCcomplicatedbyatelectasis.MethodsPre-treat-mentPET/CTscansurreperformedin36patienUwithpathologicallyprovenNSCI£cofnplic«tc6、beforeandafterPET/CTwascomparedandthechangeoftreatmentplanwa^evaluated・Thetargetvolumeswerrdelinpatcdby(TandPET/CT・ResultsPET/CTresultschangedtheclinicalstagingin18(50.0%,18/36)[xatients.PET/CTidenlifieddistantmrU3taticdiseasesin11(30.6%.11/36)parietUs,(husexcludingt7、heireligibilityforcurative3D-CRT.Oflhese11patientsfmanagementswr-rrcharigtdtopalliativeradiotherapyin3patientst8、ereduction,7withvolumeenlargementand2withlocationchange.ThreepatientsueregivenadditionalconventionaldiotherapytsincePET/CTindicater
6、beforeandafterPET/CTwascomparedandthechangeoftreatmentplanwa^evaluated・Thetargetvolumeswerrdelinpatcdby(TandPET/CT・ResultsPET/CTresultschangedtheclinicalstagingin18(50.0%,18/36)[xatients.PET/CTidenlifieddistantmrU3taticdiseasesin11(30.6%.11/36)parietUs,(husexcludingt
7、heireligibilityforcurative3D-CRT.Oflhese11patientsfmanagementswr-rrcharigtdtopalliativeradiotherapyin3patientst8、ereduction,7withvolumeenlargementand2withlocationchange.ThreepatientsueregivenadditionalconventionaldiotherapytsincePET/CTindicater
8、ereduction,7withvolumeenlargementand2withlocationchange.ThreepatientsueregivenadditionalconventionaldiotherapytsincePET/CTindicater
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