资源描述：
《曲马多对剖宫产患者术中寒战疗效的临床研究》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、曲H多对剖宫产患者术中寒战疗效的临床研究【关键词】曲马【摘要】H的比较曲马多和哌替睫对剖宫产患者术中抗寒战的效果及副作用，为英临床合理应用提供参考。方法将90例硬膜外麻醉后发生寒战产妇随机分为对照组、哌替噪组和曲马多三组，分别在发生寒战后注射生理盐水、哌替®0.5mg/kg和曲马多lmg/kg,比较注射后产妇寒战的改善程度、患者的不良反应、新生儿Apgar评分。结果应用曲马多和哌替喘后患者对寒战的明显改善率为96.6%和80.0%,两组间无明显差异，而生理盐水组明显改善率为10.0%，与曲马多和哌替唳组相比差异有显著性。哌替唳组的不良反应总体发主率明显高于曲马多
2、组和对照组。新牛儿Apgar评分哌替喘组为8.3±1.2,明显低于曲马多组的9.6±0.5和生理盐水组的9.5±0.5o结论曲马多比哌替噪更适用于治疗剖宫产患者术中寒战反应。【关键词】剖宫产术;曲马多;麻醉，硬膜外;寒战ClinicalstudyoftramadolforthetreatmentofpostepiduralanestheticshiveringinparturientsTONGLei,WANGHong-wei,CHENWu-rong,etal.(DepartmentofAnesthesiology,PutuoAffiliatedHospitalo
3、fShanghaiUnivrsityofChineseTraditionalMedicine,Shanghai200062,China)【Abstract]ObjectiveTocomparetheefficacyandsideeffectsoftramadolandpethidineforthetreatmentofpostepiduralanestheticshiveringinparturients.MethodsNinetyparturientswhoshiveredduringcesareandeliveryunderepiduralanesthesi
4、aandrequestedantishiveringtreatmentwererandomlydividedintothreegroups:GroupT(n=30)receivedtramadol1.0mg/kg,GroupP(n=30)receivedpethidine0.5mg/kg,andGroupC(n=30)received5mlofnonnalsaline.Therateofimprovementofshivering,sideeffectsandApgarscoresofnewbornswererecordedandcomparedbetweent
5、hreegroups.ResultsIngroupTandGroupP,therateofimprovementofshiveringwere29/30and24/30respectively,whileingroupCtherateofimprovementofshiveringwasonly3/30.GroupTandGroupPshowedbetterantishiveringeffectsthanGroupC(P<().()1).Nosignificantdif-ferenceofantishiveringeffectswasobservedbetwee
6、nGroupTandGroupP.TheoverallincidenceofsideeffectsinGroupPissignificantlyhigherthaninGroupTandGroupC.ApgarscoresofGroupPwas&3+1.2,significantlylowerthaninGroupTandGroupC(Pv0・05),whichwas9-6±0.5and9.5±0.5respectively.ConclusionTramadolisbettersuitedthanpethidineforthetreatmentofpostepi
7、duralanestheticshiveringinparturients.[Keywords]Cesareansection;Tramadol;Anesthesiarepidural;Shivering剖宫产患者硬膜外麻醉片寒战发生率大约在35%〜45%[1,2]。寒战会增加代谢率达400%[2],易产牛乳酸酸中毒、动脉低氧血症、眼内压增高，引起患者烦躁。在控制寒战的药物屮，哌替咙应用历史较早，但其不良反应较多。曲马多是一类非阿片类中枢镇痛约，近来才开始应用于拈抗患者术中寒战反应。木文比较了曲马多和哌替曉的抗寒战效果及副作用，为其临床合理应用提供参考。1资料与
8、方法1.1一般资料选择A
