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1、康复科病房细菌耐药监测探究作者单位：453000河南省新乡市中心医院通讯作者：张晓晖【摘要】目的了解康复科病房医院获得性细菌感染的病原菌及耐药情况。方法对笔者所在医院康复科病房2005年1月〜2009年3月所有细菌分离株及其耐药进行监测和分析。结果细菌总数503株，革兰阴性杆菌59.7%,革兰阳性球菌27.6%,真菌12.5%；革兰阳性菌中，耐甲氧西林金黄色葡萄球菌(MRSA)占金黄色葡萄球菌的99%,耐甲氧西林凝固酶阴性葡萄球菌(MRCN)占凝固酶阴性葡萄球菌94%；革兰阴性菌中，铜绿假单胞菌、嗜麦芽寡养
2、单胞菌、不动杆菌属、大肠埃希菌、黏质沙雷菌、肺炎克雷伯菌、脑膜脓毒金黄杆菌、少动鞘氨醇单胞菌、洋葱伯克霍尔德菌分别占31.4%、18%、13.7%、9.3%、6.5%、6.1%、4.7%、3.6%和2.8%,其他菌占4.1%；亚胺培南、阿米卡星、头胞他唳、环丙沙星对革兰阴性-菌的敏感率分别为58.8%.53.5%、46.1%和57.5%；万古霉素对MRSA、MRCN及肠球菌属的敏感率均为100%。结论康复科病房感染以革兰阴性菌感染为主，细菌耐药率明显升高，监测细菌分布及耐药性变化非常重要。【关键词】康复科病
3、房；医院感染；抗生素；耐药NosocomialbacterialinfectioninrehabilitationwardZHANGXiao-hui.XinxiangCentralHospital,Xinxiang453000,China[Abstract]ObjectiveToestablishtheprevalenceofnosocomialbacterialinfectionandresistanceinarehabilitationward・MethodsWeretrospectivelyanaly
4、zedallthebacterialisolatesintherehabilitationwardofourhospitalfrom2005to2009.ResultsAmongallthebacterialisolates(n503),thepercentageofGram--negativebacilli,Gram-positivesandfungiwere59.7%,27・6%and12.5%respectively.MeticillinresistantStaphylococcusaureuscou
5、ntedfor99%ofStaphylococcusaureusandmeticillinresistantcoagulasenegativeStaphylococcuscountedfor94%ofcoagulasenegativeStaphylococcus・ThepercentageofPseudomonasaeruginosa,Stenotrophomonasmaltophilia,Acinetobacterspp,Enterococcusspp,Serratiamarcescens,Klebsie
6、llapneumoniae,Chryseobacteriumspp,SphingomonaspaucimobilisandBurkholderiacepaciaaccountedfor31.4%,18%,13.7%,9.3%,6.5%,6.1%,4.7%,3.6%and2.8%ofGram-negativebacillirespectively.ThesusceptiverateofGram-negativebacteriatomipenem,amikacin,ceftazidime,ciprofloxac
7、inwere58.8%,53.5%,46.1%and57.5%respectively.Thesusceptiverateofmeticillin—resistantS.aureus,meticillinresistantcoagulasenegativeStaphylococcusandEnterococcustovancomycinwasall100%.ConclusionGram-positivesbecomeimportantpathogensofnosocomialinfection.Mostpa
8、thogensshowsignificantresistancetothemostcommonlyusedantibiotics・Itisveryimportanttomonitorthedistributionofbacteriaandtheirresistaneetoantibiotics.[Keywords]Rehabilitationcenter；Nosocomialinfection；Antibioti
