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时间:2019-11-25
《中低位Ⅱ~Ⅲ期直肠癌术前静态调强放疗和弧形调强放疗的剂量学比较研究》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、第39卷第2期新疆医科大学学报Vo1.39NO.22O16年2月JournalofXi~iangMedicalUniversityFeb.2016中低位Ⅱ~Ⅲ期直肠癌术前静态调强放疗和弧形调强放疗的剂量学比较研究曾敏,王巨武,张瑾熔,潘广鹏,阿衣古丽·哈热,马栋辉,伊斯刊达尔·阿布力米提(新疆医科大学附属肿瘤医院胸腹放疗科,乌鲁木齐830011)摘要:目的探讨直肠癌术前静态调强放疗(intensity-modulatedradiotherapy,IMRT)和弧形调强放疗(in—tensity—modulatedARC
2、therapy,IMAT)的剂量学特点,为直肠癌术前精确放疗方法的选择提供依据。方法对17例Ⅱ~Ⅲ期中低位直肠癌术前同步放化疗的患者分别进行IMRT5野、7野、9野和IMAT的计划设计,肿瘤原发病灶和转移淋巴结(GTV)及高危受累区域和区域淋巴引流区(cTV)统一给予2Gy/次、5次/w、总剂量50Gy/25次的照射。利用剂量体积直方图评价靶区剂量的分布以及危及器官的照射剂量。结果4种治疗计划均能满足靶区处方剂量及危及器官剂量限制要求,IMAT计划靶区适形指数(conformityindex,CI)优于IMRT各野计
3、划,差异有统计学意义(P4、肠肿瘤;调强放疗;弧形调强放疗;剂量学中图分类号:R735.3文献标识码:A文章编号:1009—5551(2016)02—0226-04doi:10.3969/j.issn.1009—5551.2O16.02.025Comparisonofintensity。。modulatedARCtherapywithintensity。。modulatedradiotherapyintreatmentpreoperativeradiotherapyofrectalcancerZENGMin,WANGJuwu,ZHANGJinr5、ong,PANGuangpeng,AyiguliHare,MADonghui,YisikandaerAbulimiti(DepartmentofRadiationOncology,AffiliatedTumorHospital,XinjiangMedicalUniversity,Urumqi830011,China)Abstract:ObjectiveToinvestigatethedosimetriccharacteristicofintensity—modulatedradiotherapyandintensit6、y—modulatedarctherapy(IMAT)ofthepreoperativerectalcancer.MethodsSeventeenpreopera—tivepatientswithrectaIcancerwereselectedtobetreatedwithIMRI5wild,7wild,9wildandIMATplandesign,theprimarytumorlesions,GTV,highriskofaffectedareasandCTVwereilluminatedadoseof2Gy/tim7、es。5times/w,totledoseof50Gy/25f.Usingdose~volumehistogramdatatoevaluatethedosedistributionoftargetareasandilluminatedoseoftheorganatrisk.ResultsFourkindsoftreatmentplanscanmeetthetargetprescribeddoseanddoselimitrequirementofendangerorgans.IMATplantargetCIisbett8、erthaneachwildofIMRTandthedifferencewasstatisticallysignificant(P
4、肠肿瘤;调强放疗;弧形调强放疗;剂量学中图分类号:R735.3文献标识码:A文章编号:1009—5551(2016)02—0226-04doi:10.3969/j.issn.1009—5551.2O16.02.025Comparisonofintensity。。modulatedARCtherapywithintensity。。modulatedradiotherapyintreatmentpreoperativeradiotherapyofrectalcancerZENGMin,WANGJuwu,ZHANGJinr
5、ong,PANGuangpeng,AyiguliHare,MADonghui,YisikandaerAbulimiti(DepartmentofRadiationOncology,AffiliatedTumorHospital,XinjiangMedicalUniversity,Urumqi830011,China)Abstract:ObjectiveToinvestigatethedosimetriccharacteristicofintensity—modulatedradiotherapyandintensit
6、y—modulatedarctherapy(IMAT)ofthepreoperativerectalcancer.MethodsSeventeenpreopera—tivepatientswithrectaIcancerwereselectedtobetreatedwithIMRI5wild,7wild,9wildandIMATplandesign,theprimarytumorlesions,GTV,highriskofaffectedareasandCTVwereilluminatedadoseof2Gy/tim
7、es。5times/w,totledoseof50Gy/25f.Usingdose~volumehistogramdatatoevaluatethedosedistributionoftargetareasandilluminatedoseoftheorganatrisk.ResultsFourkindsoftreatmentplanscanmeetthetargetprescribeddoseanddoselimitrequirementofendangerorgans.IMATplantargetCIisbett
8、erthaneachwildofIMRTandthedifferencewasstatisticallysignificant(P
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